来自吸水链霉菌的潮霉素B溶液
基本信息
| 产品名称 | 来自吸水链霉菌的潮霉素B溶液 |
|---|---|
| 英文名称 | Hygromycin B solution from Streptomyces hygroscopicus |
| 规格或纯度 | ≥60%（HPLC）,H₂O中45-60 mg/mL,γ辐照 |
| 运输条件 | 冰袋运输 |
| 生化机理 | 抗菌剂和抗真菌剂。作用方式：在原核生物和真核生物中，通过诱导 mRNA 模板的误读而抑制蛋白质合成。它可选择性透入因病毒感染而变得可渗透的细胞。 |
一般描述
Description
Chemical structure: aminoglycosideHygromycin B is an aminoglycoside antibiotic isolated fromStreptomyces hygroscopicus.It has been used to study protein synthesis at the level of the 70S ribosome translocation and mRNA template misreading, as an antiviral agent by selectively penetrating cells rendered permeable by virus infection and inhibiting translation, and as a selection agent for hygromycin resistance gene transformed cells. It is recommended for use as a selection agent at 100-800 μg/mL, specifically at 100 μg/mL for prokaryotes, 200 μg/mL for lower eukaryotes and 150-400 μg/mL for higher eukaryotes.
Preparation instructions
This product is a solution that is =60% (HPAE), 45-60 mg/mL in H2O, and γ-irradiated .
相关属性
| CAS编号 | 31282-04-9 |
|---|---|
| 比旋光度 | 20° (C=1,H2O) |
| 熔点 | 160-180°C |
| 储存温度 | 2-8°C储存 |
| MDL号 | MFCD06795479 |
| 分子量 | 527.52 |
| 分子式 | C20H37N3O13 |
| 品牌 | Jinpan |