Falcarinol(Synonyms: 人参炔醇; Panaxynol; Carotatoxin)

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Falcarinol (Synonyms: 人参炔醇; Panaxynol; Carotatoxin) 纯度: ≥98.0%

Falcarinol (Panaxynol) 是一种天然的、口服活性的 Hsp90 抑制剂,靶向 Hsp90 的 N 端和 C 端,具有有限的毒性。Falcarinol (Panaxynol) 诱导细胞凋亡。

Falcarinol(Synonyms: 人参炔醇; Panaxynol;  Carotatoxin)

Falcarinol Chemical Structure

CAS No. : 21852-80-2

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生物活性

Falcarinol (Panaxynol) is a natural, orally active Hsp90 inhibitor targeting both the N-terminal and C-terminal of Hsp90 with limited toxicities. Falcarinol (Panaxynol) induces apoptosis[1].

体外研究
(In Vitro)

Panaxynol inhibits the sphere-forming ability of NSCLC CSCs by inducing apoptosis. Panaxynol suppresses the viability of NSCLC cells with no effects on normal cells[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

244.37

Formula

C17H24O

CAS 号

21852-80-2

中文名称

人参炔醇

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

参考文献
  • [1]. Le HT, et al. Panaxynol, a natural Hsp90 inhibitor, effectively targets both lung cancer stem and non-stem cells. Cancer Lett. 2018 Jan 1;412:297-307.

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