N1-Acetylspermidine hydrochloride

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

N1-Acetylspermidine hydrochloride  纯度: ≥98.0%

N1-Acetylspermidine hydrochloride 是多胺的乙酰衍生物。N1-Acetylspermidine hydrochloride是多胺氧化酶 (PAO) 的底物。N1-Acetylspermidine hydrochloride 选择性升高人结直肠癌中的N1-乙酰亚精胺水平。N1-Acetylspermidine hydrochloride 在 DNA 的无嘌呤位点上具有一定的切割效率。

N1-Acetylspermidine hydrochloride

N1-Acetylspermidine hydrochloride Chemical Structure

CAS No. : 34450-16-3

规格 价格 是否有货 数量
10 mM * 1 mL in Water ￥3300 In-stock
5 mg ￥3000 In-stock
10 mg ￥4800 In-stock
50 mg   询价  
100 mg   询价  

* Please select Quantity before adding items.

N1-Acetylspermidine hydrochloride 相关产品

•相关化合物库:

  • Bioactive Compound Library Plus
  • Metabolism/Protease Compound Library
  • Anti-Cancer Compound Library
  • Food-Sourced Compound Library
  • Anti-Colorectal Cancer Compound Library

生物活性

N1-Acetylspermidine hydrochloride is an acetyl derivative of polyamine. N1-acetylspermine is the substrate for the polyamine oxidase (PAO). N1-Acetylspermidine hydrochloride selectively elevates its level in human colorectal adenocarcinomas. N1-acetylspermidine shows cleavage efficiency at apurinic sites in DNA[1][2][3].

分子量

260.20

Formula

C9H23Cl2N3O
CAS 号

34450-16-3
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
溶解性数据
In Vitro: 

H2O : 25 mg/mL (96.08 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 3.8432 mL 19.2160 mL 38.4320 mL
5 mM 0.7686 mL 3.8432 mL 7.6864 mL
10 mM 0.3843 mL 1.9216 mL 3.8432 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
参考文献

  • [1]. Royo M, et al. Mechanistic studies of mouse polyamine oxidase with N1,N12-bisethylspermine as a substrate. Biochemistry. 2005 May 10;44(18):7079-84.

    [2]. Takenoshita S, et al. Selective elevation of the N1-acetylspermidine level in human colorectal adenocarcinomas. Cancer Res. 1984 Feb;44(2):845-7.

    [3]. Haukanes BI, et al. Action of spermidine, N1-acetylspermidine, and N8-acetylspermidine at apurinic sites in DNA.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务