N-Hydroxysulfosuccinimide sodium

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N-Hydroxysulfosuccinimide sodium  纯度: ≥98.0%

N-Hydroxysulfosuccinimide (sodium) 是一种不可降解 (non-cleavable) 的 ADC linker，可用于合成抗体偶联药物 (ADC)。

N-Hydroxysulfosuccinimide sodium

N-Hydroxysulfosuccinimide sodium Chemical Structure

CAS No. : 106627-54-7

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生物活性

N-Hydroxysulfosuccinimide (sodium) is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

IC50 & Target

Non-cleavable

 

体外研究
(In Vitro)

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

217.13

Formula

C4H4NNaO6S
CAS 号

106627-54-7
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
参考文献

  • [1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

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