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Benzamidine hydrochloride (Synonyms: 苄脒盐酸盐) 纯度: ≥97.0%
Benzamidine hydrochloride 是一种可逆的,竞争性胰蛋白酶样丝氨酸蛋白酶 (trypsin-like serine proteases) 抑制剂,对 uPA、胰蛋白酶、类胰蛋白酶和 Xa 因子作用的 Ki 值分别为 97 µM, 21 µM, 20 µM 和 110 µM。
Benzamidine hydrochloride Chemical Structure
CAS No. : 1670-14-0
规格 | 价格 | 是否有货 | 数量 |
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10 mM * 1 mL in DMSO | ¥550 | In-stock | |
500 mg | ¥500 | In-stock | |
1 g | 询价 | ||
5 g | 询价 |
* Please select Quantity before adding items.
Benzamidine hydrochloride 相关产品
•相关化合物库:
- Bioactive Compound Library Plus
- Metabolism/Protease Compound Library
- Anti-Cancer Compound Library
- Fragment Library
- FDA Approved & Pharmacopeial Drug Library
- Targeted Diversity Library
生物活性 |
Benzamidine hydrochloride is an reversible competitive inhibitor of trypsin-like serine proteases, with Kis of 97 µM, 21 µM, 20 µM and 110 µM for uPA, trypsin, tryptase and factor Xa, respectively[1]. |
IC50 & Target |
Ki: 97 µM (uPA), 21 µM (trypsin), 20 µM (tryptase), 110 µM (factor Xa)[1] |
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体外研究 (In Vitro) |
Benzamidine hydrochloride has weak inhibition for tPA and thrombin, with Kis of 750 µM and 320 µM, respectively[1]. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only. |
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分子量 |
156.61 |
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Formula |
C7H9ClN2 |
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CAS 号 |
1670-14-0 |
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中文名称 |
苄脒盐酸盐 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
4°C, stored under nitrogen, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture) |
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溶解性数据 |
In Vitro:
DMSO : 100 mg/mL (638.53 mM; Need ultrasonic) H2O : 50 mg/mL (319.26 mM; Need ultrasonic) 配制储备液
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请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo:
请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
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参考文献 |
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