上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。
UNC2250 纯度: 99.22%
UNC2250 是一种有效选择性的 Mer 抑制剂,IC50为 1.7 nM,比相关的激酶 Axl 和 Tyro3 选择性高 160 倍和 60 倍。
UNC2250 Chemical Structure
CAS No. : 1493694-70-4
规格 | 价格 | 是否有货 | 数量 |
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Free Sample (0.1-0.5 mg) | Apply now | ||
10 mM * 1 mL in DMSO | ¥798 | In-stock | |
5 mg | ¥725 | In-stock | |
10 mg | ¥1200 | In-stock | |
50 mg | ¥4241 | In-stock | |
100 mg | ¥7400 | In-stock | |
200 mg | 询价 | ||
500 mg | 询价 |
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UNC2250 相关产品
•相关化合物库:
- Bioactive Compound Library Plus
- Kinase Inhibitor Library
- Protein Tyrosine Kinase Compound Library
- Anti-Cancer Compound Library
- Anti-Lung Cancer Compound Library
- Targeted Diversity Library
生物活性 |
UNC2250 is a potent and selective Mer inhibitor with an IC50 of 1.7 nM, about 160- and 60-fold selectivity over the closely related kinases Axl/Tyro3. |
IC50 & Target |
IC50: 1.7 nM (Mer)[1] |
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体外研究 (In Vitro) |
UNC2250 (5-500 nM; 1 hour) inhibits Mer phosphorylation in 697 B-ALL cells with an IC50 value of 9.8 nM[1]. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only. Western Blot Analysis[1]
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分子量 |
440.58 |
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Formula |
C24H36N6O2 |
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CAS 号 |
1493694-70-4 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
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溶解性数据 |
In Vitro:
DMSO : 20 mg/mL (45.39 mM; ultrasonic and warming and heat to 60°C) 0.1 M HCL : 12.5 mg/mL (28.37 mM; ultrasonic and adjust pH to 3 with HCl) 配制储备液
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请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 |
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参考文献 |
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