Tipiracil hydrochloride(Synonyms: 盐酸替吡嘧啶)

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Tipiracil hydrochloride (Synonyms: 盐酸替吡嘧啶) 纯度: 98.77%

Tipiracil hydrochloride 是一种胸苷磷酸化酶 (thymidine phosphorylase) 抑制剂,用于癌症研究。

Tipiracil hydrochloride(Synonyms: 盐酸替吡嘧啶)

Tipiracil hydrochloride Chemical Structure

CAS No. : 183204-72-0

规格 价格 是否有货 数量
Free Sample (0.1-0.5 mg)   Apply now  
10 mM * 1 mL in Water ¥1045 In-stock
5 mg ¥950 In-stock
10 mg ¥1350 In-stock
50 mg ¥3900 In-stock
100 mg ¥6500 In-stock
200 mg ¥9900 In-stock
500 mg   询价  
1 g   询价  

* Please select Quantity before adding items.

Tipiracil hydrochloride 相关产品

相关化合物库:

  • Drug Repurposing Compound Library Plus
  • FDA-Approved Drug Library Plus
  • FDA-Approved Drug Library Mini
  • Bioactive Compound Library Plus
  • Cell Cycle/DNA Damage Compound Library
  • FDA-Approved Drug Library
  • Anti-Cancer Compound Library
  • Anti-Aging Compound Library
  • Drug Repurposing Compound Library
  • Reprogramming Compound Library
  • Anti-COVID-19 Compound Library
  • Orally Active Compound Library
  • FDA Approved & Pharmacopeial Drug Library
  • Anti-Lung Cancer Compound Library
  • Anti-Blood Cancer Compound Library
  • Anti-Cancer Metabolism Compound Library

生物活性

Tipiracil (hydrochloride) is a thymidine phosphorylase inhibitor (TPI), used for cancer research.

体外研究
(In Vitro)

Tipiracil has antiangiogenic effect, and inhibits proliferation of endothelial cells[1]. Tipiracil is a potent inhibitor of thymidine phosphorylase, which is the enzyme that degrades FTD[2].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究
(In Vivo)

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial

分子量

279.12

Formula

C9H12Cl2N4O2

CAS 号

183204-72-0

中文名称

盐酸替吡嘧啶

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

溶解性数据
In Vitro: 

DMF : < 1 mg/mL (insoluble)

DMSO : < 1 mg/mL (insoluble or slightly soluble)

参考文献
  • [1]. Peters GJ, et al. TAS-102: more than an antimetabolite. Lancet Oncol. 2012 Dec;13(12):e518-9.

    [2]. Yoshino T, et al. TAS-102 monotherapy for pretreated metastatic colorectal cancer: a double-blind, randomised, placebo-controlled phase 2 trial. Lancet Oncol. 2012 Oct;13(10):993-1001.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务