上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。
TAK-448 acetate (Synonyms: MVT-602 acetate) 纯度: 99.37
TAK-448 acetate (MVT-602 acetate) 是一种有效的 KISS1R 激动剂,IC50 值为 460 pM,EC50 值为 632 pM。
TAK-448 acetate Chemical Structure
CAS No. : 1470374-22-1
规格 | 价格 | 是否有货 | 数量 |
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1 mg | ¥1500 | In-stock | |
5 mg | ¥4500 | In-stock | |
10 mg | 询价 | ||
50 mg | 询价 |
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TAK-448 acetate 相关产品
•相关化合物库:
- Drug Repurposing Compound Library Plus
- Clinical Compound Library Plus
- Bioactive Compound Library Plus
- Peptide Library
生物活性 |
TAK-448 acetate (MVT-602 acetate) is a potent and full KISS1R agonist with an IC50 of 460 pM and an EC50 of 632 pM[1]. |
IC50 & Target |
IC50: 460 pM (KISS1R)[1] |
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体内研究 (In Vivo) |
TAK-448 acetate (0.01-3 mg/kg; given i.h.; dosings on day 0 and 28) has greater anti-tumor effects in VCaP xenograft model[2]. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.
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Clinical Trial |
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分子量 |
1285.41 |
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Formula |
C60H84N16O16 |
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CAS 号 |
1470374-22-1 |
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Sequence Shortening |
Ac-{d-Tyr}-{Hyp}-NTF-{Aza-Gly}-L-{Arg(Me)}-W-NH2 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
Sealed storage, away from moisture
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
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溶解性数据 |
In Vitro:
DMSO : ≥ 100 mg/mL (77.80 mM) H2O : 50 mg/mL (38.90 mM; Need ultrasonic) * “≥” means soluble, but saturation unknown. 配制储备液
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请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo:
请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
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参考文献 |
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