S100A2-p53-IN-1 | 赛默飞Alfa aesar官网

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

S100A2-p53-IN-1

S100A2-p53-IN-1 (化合物 51) 是一种 S100A2-p53 相互作用抑制剂。S100A2 是一种 Ca²⁺ 结合蛋白，与细胞信号传导有关，已知在胰腺癌中上调。S100A2-p53-IN-1 可以抑制 MiaPaCa-2 胰腺癌细胞系的生长 (GI⁵⁰ of 1.2-3.4 μM)。

S100A2-p53-IN-1 Chemical Structure

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生物活性	S100A2-p53-IN-1 (compound 51) is a S100A2-p53 interactions inhibitor. S100A2 is a Ca²⁺ binding protein with implications in cell signaling and is known to be upregulated in pancreatic cancer. S100A2-p53-IN-1 can inhibit the growth of the MiaPaCa-2 pancreatic cancer cell line (GI⁵⁰ of 1.2-3.4 μM)^[1].
分子量	498.44
Formula	C₂₀H₂₀F₆N₂O₄S
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Sun J, et, al. 3,5-Bis(trifluoromethyl)phenylsulfonamides, a novel pancreatic cancer active lead. Investigation of the terminal aromatic moiety. Bioorg Med Chem Lett. 2022 Apr 1;61:128591.

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