10Z-Hymenialdisine(Synonyms: (Z)-Hymenialdisine; Hymenialdisine)

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10Z-Hymenialdisine (Synonyms: (Z)-Hymenialdisine; Hymenialdisine)

10Z-Hymenialdisine ((Z)-Hymenialdisine) 是一种天然的生物活性吡咯生物碱。10Z-Hymenialdisine 是一种泛激酶抑制剂,具有抗癌活性。

10Z-Hymenialdisine(Synonyms: (Z)-Hymenialdisine;  Hymenialdisine)

10Z-Hymenialdisine Chemical Structure

CAS No. : 82005-12-7

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生物活性

10Z-Hymenialdisine ((Z)-Hymenialdisine) is a natural bioactive pyrrole alkaloid. 10Z-Hymenialdisine is a pan kinase inhibitor, and has anticancer activities[1].

体外研究
(In Vitro)

10Z-Hymenialdisine displays a moderate effect on (ARK5, VEGFR-2, SAK and PDGFR) protein kinases. 10Z-Hymenialdisine shows a potent inhibition of RAF/MEK-1/MAPK cascade with an IC50 value of 6 nM[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

324.13

Formula

C11H10BrN5O2

CAS 号

82005-12-7

中文名称

2,5-已炔二醇;已炔二醇

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Ashraf N E Hamed, et al. Bioactive pyrrole alkaloids isolated from the Red Sea: marine sponge Stylissa carteri. Z Naturforsch C J Biosci. 2018 Apr 25;73(5-6):199-210.

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