Carubicin(Synonyms: Carminomycin; Carminomicin I)

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Carubicin (Synonyms: Carminomycin; Carminomicin I)

Carubicin (Carminomycin) 是一种微生物衍生的化合物。Carubicin 是 VHL 缺陷型 (VHL-/-) CCRCC 细胞增殖的有效抑制剂。Carubicin 还通过独立于 p53 或缺氧诱导因子 HIF2 的机制诱导细胞凋亡 (apoptosis)。Carubicin 具有研究癌症疾病的潜力。

Carubicin(Synonyms: Carminomycin;  Carminomicin I)

Carubicin Chemical Structure

CAS No. : 50935-04-1

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Carubicin 的其他形式现货产品:

Carubicin hydrochloride

生物活性

Carubicin (Carminomycin) is a microbially-derived compound. Carubicin is an effective inhibitor of VHL-defective (VHL−/−) CCRCC cell proliferation. Carubicin also induces apoptosis by a mechanism independent of p53 or hypoxia-inducible factor HIF2. Carubicin has the potential for the research of cancer diseases[1][2].

分子量

513.49

Formula

C26H27NO10

CAS 号

50935-04-1

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. [1]Woldemichael GM, et al. Carminomycin I is an apoptosis inducer that targets the Golgi complex in clear cell renal carcinoma cells. Cancer Res. 2011 Jan 1;71(1):134-42.

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