AKT-IN-10

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

AKT-IN-10 

AKT-IN-10 是一种有效的 AKT 抑制剂。蛋白激酶 B (PKB,也称为 AKT) 是细胞中 PI3K/AKT/mTOR 信号传导的核心,其功能对细胞生长、存活、分化和代谢很重要。AKT-IN-10 具有研究乳腺癌和前列腺癌的潜力 (摘自专利 WO2021185238A1,化合物 4)。

AKT-IN-10

AKT-IN-10 Chemical Structure

CAS No. : 2709045-56-5

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生物活性

AKT-IN-10 is a potent inhibitor of AKT. Protein kinase B (PKB, also known as AKT) is central to PI3K/AKT/mTOR signaling in cells, and its function is important for cell growth, survival, differentiation and metabolism. AKT-IN-10 has the potential for the research of breast and prostate cancer (extracted from patent WO2021185238A1, compound 4)[1].

IC50 & Target

AKT[1]

分子量

484.03

Formula

C26H34ClN5O2

CAS 号

2709045-56-5

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Xin Li, et al. Thickened dicyclic derivatives, their preparation methods and their application in medicine. Patent WO2021185238A1.

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