上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。
OM-1700
OM-1700 是一种有效的 tankyrase 抑制剂，对 tankyrase 1 和 tankyrase 2 的 IC50 分别为 127 和 14 nM。OM-1700 减少结肠癌细胞系 COLO 320DM (GI50= 650 nM) 细胞生长。
OM-1700 Chemical Structure
CAS No. : 2406276-78-4
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| 生物活性 |
OM-1700 is a potent tankyrase inhibitor with IC50s of 127 and 14 nM for tankyrase 1 and tankyrase 2, respectively. OM-1700 reduces cell growth in the colon cancer cell line COLO 320DM (GI50=650 nM)[1]. |
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| IC50 & Target[1] |
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| 体外研究 (In Vitro) |
OM-153 shows inhibition (IC50=19 nM) in a cellular (HEK293) WNT/β-catenin signaling reporter assay[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. |
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| 分子量 |
458.49 |
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| Formula |
C25H23FN6O2 |
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| CAS 号 |
2406276-78-4 |
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| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
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| 储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
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| 参考文献 |
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