HDAC6-IN-3 | 赛默飞Alfa aesar官网

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HDAC6-IN-3

HDAC6-IN-3 (Compound 14) 是一种抗前列腺癌药物，是一种有效的、具有口服活性的 HDAC6 抑制剂，对 HDAC1/2/3/6/8/10 的 IC₅₀ 范围为 0.02-1.54 μM。HDAC6-IN-3 也是一种有效的 MAO-A (IC₅₀=0.79 μM) 和 LSD1 抑制剂。

HDAC6-IN-3 Chemical Structure

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生物活性	HDAC6-IN-3 (Compound 14), an antiprostate cancer agent, is a potent, orally active HDAC6 inhibitor with IC₅₀s ranging from 0.02-1.54 μM for HDAC1/2/3/6/8/10. HDAC6-IN-3 is also an effective MAO-A (IC₅₀=0.79 μM) and LSD1 inhibitor^[1].
分子量	345.44
Formula	C₁₉H₂₇N₃O₃
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Ojha R, et al. Installation of Pargyline, a LSD1 Inhibitor, in the HDAC Inhibitory Template Culminated in the Identification of a Tractable Antiprostate Cancer Agent. J Med Chem. 2021;64(24):17824-17845.

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