N-ε-propargyloxycarbonyl-L-lysine hydrochloride(Synonyms: H-​L-​Lys(Poc)​-​OH hydrochloride)

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N-ε-propargyloxycarbonyl-L-lysine hydrochloride (Synonyms: H-​L-​Lys(Poc)​-​OH hydrochloride)

N-ε-propargyloxycarbonyl-L-lysine (H-L-Lys(Poc)-OH) hydrochloride 是一种基于赖氨酸的非天然氨基酸 (UAA)。N-ε-propargyloxycarbonyl-L-lysine 广泛用于多种生物体中荧光探针的生物偶联。

N-ε-propargyloxycarbonyl-L-lysine hydrochloride(Synonyms: H-​L-​Lys(Poc)​-​OH hydrochloride)

N-ε-propargyloxycarbonyl-L-lysine hydrochloride Chemical Structure

CAS No. : 1428330-91-9

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生物活性

N-ε-propargyloxycarbonyl-L-lysine (H-L-Lys(Poc)-OH) hydrochloride is a lysine-based unnatural amino acid (UAA). N-ε-propargyloxycarbonyl-L-lysine is widely used for bio-conjugation of fluorescent probes in diverse organisms from E. coli to mammalian cells even in animals[1][2].

体外研究
(In Vitro)

Labeling of N-ε-propargyloxycarbonyl-L-lysine (H-L-Lys(Poc)-OH) hydrochloride-carrying cellular proteins, such as Sec61β, Htt74Q and the histone H3 variant H3.3, with a sensitive Raman tag by click chemistry for molecular hyperspectral SRS imaging[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

264.71

Formula

C10H17ClN2O4

CAS 号

1428330-91-9

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Kyung Jin Lee, et al. Site-Specific Labeling of Proteins Using Unnatural Amino Acids. Mol Cells. 2019 May 31;42(5):386-396.

    [2]. Enke HEIKE, et al. Modified microcystins and nodularins.WO2018206715A2

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