(2S,3R)-Voruciclib

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(2S,3R)-Voruciclib 

(2S,3R)-Voruciclib 是 Voruciclib 的 (2S,3R)-对映异构体。(2S,3R)-Voruciclib 是一种具有口服活性的 CDK 抑制剂。

(2S,3R)-Voruciclib

(2S,3R)-Voruciclib Chemical Structure

CAS No. : 1253731-24-6

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生物活性

(2S,3R)-Voruciclib is the (2S,3R)-enantiomer of Voruciclib. (2S,3R)-Voruciclib is an orally active CDK inhibitor[1].

IC50 & Target

CDK[1]

体外研究
(In Vitro)

(2S,3R)-Voruciclib (Compound B, formula I) is used in combination with a compound capable of inhibiting EGFR kinase activity and Gemcitabine to treat pancreatic cancer[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

469.84

Formula

C22H19ClF3NO5

CAS 号

1253731-24-6

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Veena Agarwal, et al. A synergistic pharmaceutical combination for the treatment of pancreatic cancer. WO2012123889A1.

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