c-Fms-IN-9 | 赛默飞Alfa aesar官网

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

c-Fms-IN-9

c-Fms-IN-9 是一种 c-FMS 抑制剂，详细信息请参考专利文献 WO2014145023A1 中的化合物 Example 7。c-Fms-IN-9 抑制非磷酸化的 c-FMS 激酶 (uFMS) 和 uKIT，IC₅₀ 分别为 <0.01 μM 和 0.1-1 μM。

c-Fms-IN-9 Chemical Structure

CAS No. : 1628574-50-4

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250 mg		询价
500 mg		询价

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生物活性	c-Fms-IN-9 is a c-FMS inhibitor extracted from patent WO2014145023A1, Compound Example 7. c-Fms-IN-9 inhibits unphosphorylated c-FMS kinase (uFMS) and uKIT with IC₅₀s of <0.01 μM and 0.1-1 μM, respectively^[1].
IC₅₀ & Target	c-FMS^[1]
体外研究 (In Vitro)	c-Fms-IN-9 inhibits M-NFS-60, THP-1 and osteoclast cells proliferation with IC₅₀s of 0.01-0.1 μM^[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量	405.45
Formula	C₂₁H₂₃N₇O₂
CAS 号	1628574-50-4
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Gary E. L. BRANDT, et al. 1,2,4-triazol-5-ones and analogs exhibiting anti-cancer and anti-proliferative activities. WO2014145023A1.

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