H3K27(Me) (15-34)

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H3K27(Me) (15-34) 

H3K27(Me) (15-34) 是一种源自人组蛋白的组蛋白肽,也是一种阻遏标记。PRC2 可催化 H3K27(Me) 的甲基化。

H3K27(Me) (15-34)

H3K27(Me) (15-34) Chemical Structure

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生物活性

H3K27(Me) (15-34), a histone peptide, is a repressive chromatin markderived from human histone. Polycomb Repressive Complex 2 (PRC2) is a multiprotein complex that catalyzes the methylation of H3K27(Me)[1][2].

分子量

1994.34

Formula

C85H152N30O25

Sequence

Ala-Pro-Arg-Lys-Gln-Leu-Ala-Thr-Lys-Ala-Ala-Arg-{Lys(Me)}-Ser-Ala-Pro-Ala-Thr-Gly-Gly

Sequence Shortening

APRKQLATKAAR-{Lys(Me)}-SAPATGG

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Elizabeth T Wiles, et al. H3K27 Methylation: A Promiscuous Repressive Chromatin Mark. Curr Opin Genet Dev. 2017 Apr;43:31-37.

    [2]. Brian P Chadwick, et al. Multiple Spatially Distinct Types of Facultative Heterochromatin on the Human Inactive X Chromosome. Proc Natl Acad Sci U S A. 2004 Dec 14;101(50):17450-5.

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