2-Keto-D-galactose(Synonyms: D-半乳糖酮; D-​Galactosone)

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

2-Keto-D-galactose (Synonyms: D-半乳糖酮; D-​Galactosone)

2-Keto-D-galactose (D-Galactosone) 抑制 DNA 合成，并抑制生长的 Ehrlich 腹水肿瘤细胞增殖。

2-Keto-D-galactose(Synonyms: D-半乳糖酮; D-​Galactosone)

2-Keto-D-galactose Chemical Structure

CAS No. : 54142-77-7

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生物活性

2-Keto-D-galactose (D-Galactosone) inhibits DNA synthesis, and inhibits proliferation of in vitro grown Ehrlich ascites tumor cells[1].

IC50 & Target

DNA synthesis[1]
体外研究
(In Vitro)

2 mM 2-Keto-D-galactose (Galactosone) causes a comparable inhibition of DNA synthesis. Proliferation of in vitro grown Ehrlich ascites tumor cells is completely inhibited by 1-2 mM 2-Keto-D-galactose without severely affecting viability (dye exclusion test); no phase-specific arrest of cell growth is observed[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

178.14

Formula

C6H10O6
CAS 号

54142-77-7
中文名称

2-酮-D-半乳糖；D-半乳糖酮
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Reiffen KA, et al. A comparative study on proliferation, macromolecular synthesis and energy metabolism of in vitro-grown Ehrlich ascites tumor cells in the presence of glucosone, galactosone and methylglyoxal. J Cancer Res Clin Oncol. 1984;107(3):206-10.

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