(Rac)-Plevitrexed(Synonyms: (Rac)-ZD 9331; (Rac)-BGC9331)

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(Rac)-Plevitrexed (Synonyms: (Rac)-ZD 9331; (Rac)-BGC9331)

(Rac)-Plevitrexed ((Rac)-ZD 9331; (Rac)-BGC9331) 是 Plevitrexed 的外消旋体。Plevitrexed 是口服有效的胸苷酸合酶 (TS) 抑制剂。

(Rac)-Plevitrexed(Synonyms: (Rac)-ZD 9331; (Rac)-BGC9331)

(Rac)-Plevitrexed Chemical Structure

CAS No. : 153538-08-0

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生物活性

(Rac)-Plevitrexed ((Rac)-ZD 9331; (Rac)-BGC9331) is a racemate of Plevitrexed. Plevitrexed is an orally active and potent thymidylate synthase (TS) inhibitor.

分子量

532.53

Formula

C26H25FN8O4
CAS 号

153538-08-0
中文名称

(Rac)-普来曲塞
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Tochowicz A, et al. Development and binding mode assessment of N-[4-[2-propyn-1-yl[(6S)-4,6,7,8-tetrahydro-2-(hydroxymethyl)-4-oxo-3H-cyclopenta[g]quinazolin-6-yl]amino]benzoyl]-l-γ-glutamyl-D-glutamic acid (BGC 945), a novel thymidylate synthase inhibitor that targets tumor cells. J Med Chem. 2013 Jul 11;56(13):5446-55.

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