IACS-8803 diammonium

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上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

IACS-8803 diammonium  纯度: 99.24%

IACS-8803 diammonium 是一种高效环状二核苷酸的 STING 激动剂，具有强大的全身抗肿瘤作用。

IACS-8803 diammonium

IACS-8803 diammonium Chemical Structure

规格 价格 是否有货 数量
1 mg ￥5500 In-stock
5 mg ￥14500 In-stock
10 mg   询价  
50 mg   询价  

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IACS-8803 diammonium 相关产品

•相关化合物库:

  • Bioactive Compound Library Plus
  • Macrocyclic Compound Library

生物活性

IACS-8803 diammonium is a highly potent cyclic dinucleotide STING agonist. IACS-8803 diammonium has a robust systemic antitumor efficacy[1].

体内研究
(In Vivo)

IACS-8803 diammonium (10 µg; intra-tumoral injection) shows superior antitumor activity in mice bearing bilateral B16-OVA melanomas[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

726.60

Formula

C20H29FN12O9P2S2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
参考文献

  • [1]. Ager CR, et al. Discovery of IACS-8803 and IACS-8779, potent agonists of stimulator of interferon genes (STING) with robust systemic antitumor efficacy. Bioorg Med Chem Lett. 2019 Oct 15;29(20):126640.

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