LB-60-OF61 hydrochloride

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

LB-60-OF61 hydrochloride 

LB-60-OF61 hydrochloride 是一种有效的 NAMPT 抑制剂，LB-60-OF61 hydrochloride 是一种对 MYC 过表达细胞系具有选择性的细胞毒性化合物。

LB-60-OF61 hydrochloride

LB-60-OF61 hydrochloride Chemical Structure

CAS No. : 742064-38-6

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

LB-60-OF61 hydrochloride is a potent NAMPT (nicotinamide phosphoribosyltransferase) inhibitor. LB-60-OF61 hydrochloride is a cytotoxic compound with a selectivity towards MYC overexpressing cell lines[1].

体外研究
(In Vitro)

LB-60-OF61 is potent against HCT116 cells with an IC50 around 30 nM as measured in a 384 well format[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

531.05

Formula

C29H31ClN6O2
CAS 号

742064-38-6
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Estoppey D, et al. Identification of a novel NAMPT inhibitor by CRISPR/Cas9 chemogenomic profiling in mammalian cells. Sci Rep. 2017;7:42728. Published 2017 Feb 16.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务