(S,R,S)-AHPC-Me-C5-COOH

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

(S,R,S)-AHPC-Me-C5-COOH  纯度: 96.19%

(S,R,S)-AHPC-Me-C5-COOH 是一种合成的 E3 连接酶配体结合物，它结合了 VHL 配体和 linker。(S,R,S)-AHPC-Me-C5-COOH 可用于 PROTAC DT2216 (HY-130604)。

(S,R,S)-AHPC-Me-C5-COOH

(S,R,S)-AHPC-Me-C5-COOH Chemical Structure

CAS No. : 2229976-21-8

规格 价格 是否有货 数量
50 mg ￥9600 In-stock
100 mg ￥15500 In-stock
200 mg   询价  
500 mg   询价  

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生物活性

(S,R,S)-AHPC-Me-C5-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the a VHL ligand and a linker. (S,R,S)-AHPC-Me-C5-COOH can be used in PROTAC DT2216 (HY-130604)[1].

IC50 & Target[1]

VHL

 

体外研究
(In Vitro)

DT2216 is a selective B-cell lymphoma extra large (BCL-XL) PROTAC degrader[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

586.74

Formula

C30H42N4O6S
CAS 号

2229976-21-8
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
参考文献

  • [1]. Khan S, et al. A selective BCL-XL PROTAC degrader achieves safe and potent antitumor activity. Nat Med. 2019 Dec;25(12):1938-1947.

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