DMEA-PNU-159682

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

DMEA-PNU-159682 

DMEA-PNU-159682 (molecule D12) 是一种 ADC 细胞毒素分子,包括来自肝微粒体的新霉素代谢产物 (MMDX) 和有效的 ADC 细胞毒素 PNU-159682。

DMEA-PNU-159682

DMEA-PNU-159682 Chemical Structure

CAS No. : 1799421-48-9

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生物活性

DMEA-PNU-159682 (molecule D12) is a ADC cytotoxin molecule including metabolites of nemorubicin (MMDX) from liver microsomes and a potent ADCs cytotoxin PNU-159682[1][2].

IC50 & Target[1]

Daunorubicins/Doxorubicins

 

分子量

755.76

Formula

C37H45N3O14

CAS 号

1799421-48-9

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Chen Jingkang, et al. Disubstituted maleic amide class connexon for antibody-drug conjugate and its preparation method and application. CN108101825A.

    [2]. John Flygare, et al. Anthracycline disulfide intermediates, antibody-drug conjugates and methods. WO2016040825A1

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