MC-Val-Cit-PAB-dimethylDNA31

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上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

MC-Val-Cit-PAB-dimethylDNA31 

MC-Val-Cit-PAB-dimethylDNA31 是抗体偶联药物的一部分，由 dimethylDNA31 和 ADC linker MC-Val-Cit-PAB 连接而成。DimethylDNA31 具有针对持久性和固定相金黄色葡萄球菌有效的杀菌活性。

MC-Val-Cit-PAB-dimethylDNA31

MC-Val-Cit-PAB-dimethylDNA31 Chemical Structure

CAS No. : 1639352-06-9

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生物活性

MC-Val-Cit-PAB-dimethylDNA31 is a drug-linker conjugate for ADC with potent antitumor activity by using dimethylDNA31, linked via the ADC linker MC-Val-Cit-PAB. DimethylDNA31 has effective bactericidal activity against persisters and stationary-phase S. aureus.

IC50 & Target

Traditional Cytotoxic Agents

 

分子量

1482.69

Formula

C78H101N10O19+
CAS 号

1639352-06-9
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Staben LR, et al. Targeted drug delivery through the traceless release of tertiary and heteroaryl amines from antibody-drug conjugates. Nat Chem. 2016 Dec;8(12):1112-1119.

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