Pomalidomide-amido-C4-amido-C6-NH-Boc(Synonyms: Cereblon Ligand-Linker Conjugates 21; E3 Ligase Ligand-Linker Conjugates 54)

发表于由

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Pomalidomide-amido-C4-amido-C6-NH-Boc (Synonyms: Cereblon Ligand-Linker Conjugates 21; E3 Ligase Ligand-Linker Conjugates 54)

Pomalidomide-amido-C4-amido-C6-NH-Boc 是一种合成的 E3 连接酶配体-linker 偶联物，包含基于 Pomalidomide 的 cereblon 配体和 1 个 linker。

Pomalidomide-amido-C4-amido-C6-NH-Boc(Synonyms: Cereblon Ligand-Linker Conjugates 21; E3 Ligase Ligand-Linker Conjugates 54)

Pomalidomide-amido-C4-amido-C6-NH-Boc Chemical Structure

CAS No. : 2435808-02-7

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生物活性

Pomalidomide-amido-C4-amido-C6-NH-Boc is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology.

IC50 & Target

Cereblon

 

分子量

599.68

Formula

C30H41N5O8
CAS 号

2435808-02-7
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Wang Z, et al. Proteolysis Targeting Chimeras for the Selective Degradation of Mcl-1/Bcl-2 Derived from Nonselective Target Binding Ligands. J Med Chem. 2019 Aug 21.

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