Pomalidomide-amido-C4-amido-PEG2-C2-NH-Boc(Synonyms: Cereblon Ligand-Linker Conjugates 20; E3 Ligase Ligand-Linker Conjugates 53)

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

Pomalidomide-amido-C4-amido-PEG2-C2-NH-Boc (Synonyms: Cereblon Ligand-Linker Conjugates 20; E3 Ligase Ligand-Linker Conjugates 53)

Pomalidomide-amido-C4-amido-PEG2-C2-NH-Boc 是一种合成的 E3 连接酶配体-linker 偶联物，包含基于 Pomalidomide 的 cereblon 配体和 2 个单元 PEG 的 linker。

Pomalidomide-amido-C4-amido-PEG2-C2-NH-Boc(Synonyms: Cereblon Ligand-Linker Conjugates 20; E3 Ligase Ligand-Linker Conjugates 53)

Pomalidomide-amido-C4-amido-PEG2-C2-NH-Boc Chemical Structure

CAS No. : 2435720-04-8

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生物活性

Pomalidomide-amido-C4-amido-PEG2-C2-NH-Boc is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 2-unit PEG linker used in PROTAC technology.

IC50 & Target

Cereblon

 

分子量

631.67

Formula

C30H41N5O10
CAS 号

2435720-04-8
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Wang Z, et al. Proteolysis Targeting Chimeras for the Selective Degradation of Mcl-1/Bcl-2 Derived from Nonselective Target Binding Ligands. J Med Chem. 2019 Aug 21.

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