(±)-H3RESCA-TFP(Synonyms: (±)-H3L28)

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(±)-H3RESCA-TFP (Synonyms: (±)-H3L28)

(±)-H3RESCA-TFP ((±)-H3L28) 是一种约束络合剂 (RESCA) 的四氟苯基酯衍生物。(±)-H3RESCA-TFP 可用于通过胺偶联 (例如,N 末端和/或赖氨酸的 ε-氨基) 使螯合剂与生物分子偶联。

(±)-H3RESCA-TFP(Synonyms: (±)-H3L28)

(±)-H3RESCA-TFP Chemical Structure

CAS No. : 1919794-40-3

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5 mg ¥5800 询问价格 & 货期
10 mg ¥8500 询问价格 & 货期
50 mg ¥19000 询问价格 & 货期
100 mg ¥28000 询问价格 & 货期

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生物活性

(±)-H3RESCA-TFP ((±)-H3L28) is a tetrafluorophenyl ester derivative of restrained complexing agent (RESCA). (±)-H3RESCA-TFP can be used to conjugate the chelator with a biomolecule via amine coupling (e.g., N terminus and/or the ε-amino groups of lysine)[1].

体外研究
(In Vitro)

The aluminum fluoride restrained complexing agent (Al18F-RESCA) method combines the chemical advantages of a chelator-based radiolabeling method with the unique physical properties of the radionuclide of choice, fluorine-18. Proteins of interest can be conjugated to RESCA via amine coupling using (±)-H3RESCA-TFP. Al18F-labeled proteins can be obtained with moderate (12-17 GBq/µmol) to good (80-85 GBq/µmol) apparent molar activity, depending on the starting activity of 18F[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

584.51

Formula

C27H28F4N2O8

CAS 号

1919794-40-3

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Cleeren F, et al. Direct fluorine-18 labeling of heat-sensitive biomolecules for positron emission tomography imaging using the Al18F-RESCA method. Nat Protoc. 2018 Oct;13(10):2330-2347.

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