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Asperphenamate 纯度: ≥98.0%
Asperphenamate 是来自Aspergillus flatiipes 的真菌代谢物,具有抗肿瘤活性,其对 T47D、MDA-MB-231 和 HL-60 细胞的IC50 值分别为 92.3 μM、96.5 μM 和97.9 μM。
Asperphenamate Chemical Structure
CAS No. : 63631-36-7
规格 | 价格 | 是否有货 | 数量 |
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5 mg | ¥5800 | In-stock | |
10 mg | ¥8000 | In-stock | |
50 mg | 询价 | ||
100 mg | 询价 |
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Asperphenamate 相关产品
•相关化合物库:
- Natural Product Library Plus
- Bioactive Compound Library Plus
- Anti-Infection Compound Library
- Immunology/Inflammation Compound Library
- Metabolism/Protease Compound Library
- Natural Product Library
- Anti-Cancer Compound Library
- Autophagy Compound Library
- Microbial Metabolite Library
- Angiogenesis Related Compound Library
生物活性 |
Asperphenamate, a fungal metabolite of Aspergillus flatiipes with anti-cancer effect, exhibits IC50 values of 92.3 μM, 96.5 μM and 97.9 μM in T47D, MDA-MB-231 and HL-60 cells, respectively[1][2]. |
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体外研究 (In Vitro) |
Asperphenamate can inhibit cancer cell proliferation by fully inducing autophagy. asperphenamate showed inhibition effects against cathepsin L. At the same time, it also displayed weak inhibitory ability against cathepsin S. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. |
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分子量 |
506.59 |
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Formula |
C32H30N2O4 |
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CAS 号 |
63631-36-7 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
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溶解性数据 |
In Vitro:
DMSO : 100 mg/mL (197.40 mM; Need ultrasonic) 配制储备液
*
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo:
请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
*以上所有助溶剂都可在 Shanghai Jinpan Biotech Co Ltd 网站选购。
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参考文献 |
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