Aminobenzenesulfonic auristatin E

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Aminobenzenesulfonic auristatin E 

Aminobenzenesulfonic auristatin E 是抗体偶联药物的一部分,由细胞毒性微管蛋白修饰剂 Auristatin E 和 ADC linker Aminobenzenesulfonic 连接而成。

Aminobenzenesulfonic auristatin E

Aminobenzenesulfonic auristatin E Chemical Structure

CAS No. : 1800462-99-0

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生物活性

Aminobenzenesulfonic auristatin E is a drug-linker conjugate for ADC with potent antitumor activity by using Auristatin E (a cytotoxic tubulin modifier), linked via the ADC linker Aminobenzenesulfonic[1].

IC50 & Target[1]

Auristatin

 

体外研究
(In Vitro)

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

753.00

Formula

C37H64N6O8S

CAS 号

1800462-99-0

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Kevin HAMBLETT, et al. Anti-her2 biparatopic antibody-drug conjugates and methods of use.

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