Cdc7-IN-8

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Cdc7-IN-8 

Cdc7-IN-8 是 Cdc7 的有效抑制剂。Cdc7 是一种丝氨酸/苏氨酸激酶,它通过磷酸化微染色体维持蛋白 (MCM 蛋白) 来激活 MCM 促进作用,该蛋白是 DNA 复制引发剂的重要元素。Cdc7-IN-8 具有研究癌症疾病的潜力 (摘自专利 WO2021032170A1,化合物 1-1/1-2)。

Cdc7-IN-8

Cdc7-IN-8 Chemical Structure

CAS No. : 2606780-38-3

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生物活性

Cdc7-IN-8 is a potent inhibitor of Cdc7. Cdc7 is a serine/threonine kinase which activates MCM promotion by phosphorylating the microchromosome maintenance protein (MCM protein), an important element of the DNA replication initiator. Cdc7-IN-8 has the potential for the research of cancer diseases (extracted from patent WO2021032170A1, compound 1-1/1-2)[1].

分子量

351.40

Formula

C19H21N5O2

CAS 号

2606780-38-3

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Lun Lu, et al. Tetracyclic compound used as cdc7 inhibitor. Patent WO2021032170A1.

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