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Darinaparsin (Synonyms: ZIO-101; S-Dimethylarsino-glutathione)
Darinaparsin (ZIO-101) 是一种有机砷，是一种线粒体靶向剂。Darinaparsin 可诱导癌细胞凋亡 (apoptosis)，并具有抗癌作用。
Darinaparsin Chemical Structure
CAS No. : 69819-86-9
| 规格 | 是否有货 | ||
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| 100 mg | 询价 | ||
| 250 mg | 询价 | ||
| 500 mg | 询价 |
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| 生物活性 |
Darinaparsin (ZIO-101), an organic arsenical, is a mitochondrial-targeted agent. Darinaparsin induces apoptosis in ancer cells, and has anticancer effects[1]. |
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| 体外研究 (In Vitro) |
Darinaparsin is cytotoxic to prostate cancer cell lines as well as fresh prostate cancer cells at low micromolar concentrations, and importantly inhibits the termed tumor-initiating cells (TIC) subpopulations[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. |
| 体内研究 (In Vivo) |
Darinaparsin inhibits growth of the castrate-resistant Du145 prostate tumor propagated as xenograft in mice and inhibits the tumor-initiating potential of prostate cancer cells[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. |
| 分子量 |
411.31 |
| Formula |
C12H22AsN3O6S |
| CAS 号 |
69819-86-9 |
| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
| 储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
| 参考文献 |
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