Cas(154589-96-5), Stauprimide, ,Stauprimide,

发表于由

Stauprimide,抑制剂

抑制NME2核易位；灌注ESC以分化
99%

有货

Cas(154589-96-5), Stauprimide, ,Stauprimide,

CAS编号 154589-96-5 | 品牌：Jinpan
Stauprimide

MSDS

质检证书(CoA)

相似产品

  • 分子式 C35H28N4O5
  • 分子量584.62
  • PubChem编号 46245328

货号 (SKU) 包装规格 是否现货 价格 数量
S139814-1mg 1mg 现货 Cas(154589-96-5), Stauprimide, ,Stauprimide,  
S139814-5mg 5mg 现货 Cas(154589-96-5), Stauprimide, ,Stauprimide,  

基本信息

产品名称 Stauprimide,抑制剂
英文名称 Stauprimide
别名 N-Benzoyl-7-oxostaurosporine
英文别名 N-Benzoyl-7-oxostaurosporine
规格或纯度 99%
运输条件 超低温冰袋运输
生化机理 引发胚胎干细胞（ESC）分化的小分子。与NME2相互作用并抑制其核易位。提高小鼠和人ESCs体外定向分化的效率。

一般描述

Stauprimide is an indolocarbazole semi-synthetic small molecule shown to significantly increase the efficiency of directed embryonic stem cell differentiation. Stauprimide inhibits the nuclear localization of NME2, blocking and downregulating c-Myc expression. The expression of c-Myc is crucial for embryonic stem cell self-renewal, and intervention by Stauprimide allows for more efficient lineage-specific differentiation. NME2 is also indicated to be upregulated in certain cancers, indicating further application for the blocking action of StauprimideAn indolocarbazole promoter of embryonic stem cell differentiation.

Stauprimide is an indolocarbazole semi-synthetic small molecule shown to significantly increase the efficiency of directed embryonic stem cell differentiation. Stauprimide inhibits the nuclear localization of NME2, blocking and downregulating c-Myc expression. The expression of c-Myc is crucial for embryonic stem cell self-renewal, and intervention by Stauprimide allows for more efficient lineage-specific differentiation. NME2 is also indicated to be upregulated in certain cancers, indicating further application for the blocking action of Stauprimide
An indolocarbazole promoter of embryonic stem cell differentiation.

相关属性

CAS编号 154589-96-5
敏感性 对光敏感
熔点 145°C
溶解性 Soluble in DMSO}
储存温度 -20°C储存
分子量 584.62
分子式 C35H28N4O5
品牌 Jinpan
PubChem CID 46245328