Cas(58-58-2), 嘌呤霉素盐酸盐, 二氢氯化嘌呤毒素,Puromycin dihydrochloride,

发表于由

嘌呤霉素盐酸盐

氨基核酸酶抗生素剂。蛋白质生物合成抑制剂。
≥98%

有货

Cas(58-58-2), 嘌呤霉素盐酸盐, 二氢氯化嘌呤毒素,Puromycin dihydrochloride,

CAS编号 58-58-2 | 品牌：Jinpan
Puromycin dihydrochloride

MSDS

质检证书(CoA)

相似产品

  • 分子式 C22H29N7O5·2HCl
  • 分子量544.44
  • Beilstein号 3853613
  • EC号 200-387-8
  • MDL号 MFCD00012691
  • PubChem编号 443311

货号 (SKU) 包装规格 是否现货 价格 数量
P113126-5mg 5mg 现货 Cas(58-58-2), 嘌呤霉素盐酸盐, 二氢氯化嘌呤毒素,Puromycin dihydrochloride,  
P113126-25mg 25mg 现货 Cas(58-58-2), 嘌呤霉素盐酸盐, 二氢氯化嘌呤毒素,Puromycin dihydrochloride,  
P113126-100mg 100mg 现货 Cas(58-58-2), 嘌呤霉素盐酸盐, 二氢氯化嘌呤毒素,Puromycin dihydrochloride,  
P113126-500mg 500mg 现货 Cas(58-58-2), 嘌呤霉素盐酸盐, 二氢氯化嘌呤毒素,Puromycin dihydrochloride,  

基本信息

产品名称 嘌呤霉素盐酸盐
英文名称 Puromycin dihydrochloride
别名 二氢氯化嘌呤毒素；嘌呤霉素二盐酸盐
英文别名 3′-[α-Amino-p-methoxyhydrocinnamamido]-3′-deoxy-N,N-dimethyladenosine dihydrochloride ;Stylomycin hydrochloride；CL13900 dihydrochloride
规格或纯度 ≥98%
运输条件 超低温冰袋运输
生化机理 Puromycin is an aminonuclease antibiotic used for selection and maintenance of cell lines expressing a transfected pac gene, whose product, puromycin-N-acetyl-transferase, inactivates puromycin via acetylation. This product has been cell culture tested and is recommended for selection of stably transfected cells following transfection with Santa Cruz Biotechnology shRNA or Lentiviral particles. BACKGROUND: Puromycin is an antibiotic substance produced by the soil actinomycete Streptomyces alboniger which induces apoptosis in cells by interfering with RNA function, leading to inhibition of protein synthesis. Toxic to both eukaryotic and prokaryotic cells. Believed to act as an acyl-tRNA analogue causing premature chain termination, it has been shown to arrest cells in G2/M phase.Aminonuclease antibiotic agent. Protein biosynthesis inhibitor. Induces cell cycle arrest in G2/M phase and apoptosis. Inhibits transport of proteins into mitochondria. Inhibits translation in vivo .

一般描述

Puromycin 2HCl 是一种氨基核苷抗菌素，其可作为蛋白质合成的抑制剂。An aminonuclease antibiotic used for selection and maintenance of cell lines expressing a transfected pac gene.

Puromycin 2HCl is an aminonucleoside antibiotic, which acts as a protein synthesis inhibitor.
An aminonuclease antibiotic used for selection and maintenance of cell lines expressing a transfected pac gene.

相关属性

CAS编号 58-58-2
敏感性 对热、湿度、光敏感
熔点 174°C(lit.)
溶解性 Soluble in water (50 mg/ml), ethanol (~1 mg/ml), DMSO (~13 mg/ml), DMF (~14 mg/ml), and PBS, pH 7.2 (~10 mg/ml).
储存温度 避光,-20°C储存
Reaxys-RN 3853613
RTECS AU7355000
MDL号 MFCD00012691
分子量 544.44
分子式 C22H29N7O5·2HCl
EC号 200-387-8
品牌 Jinpan
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关联CAS 53-79-2
PubChem CID 443311