盐酸洛美沙星
10mM in Water
有货
基本信息
| 产品名称 | 盐酸洛美沙星 |
|---|---|
| 英文名称 | Lomefloxacin hydrochloride |
| 别名 | (±)-1-乙基-6,8-二氟-1,4-二氢-7-(3-甲基-1-哌嗪基)-4-氧-喹啉-3-羧酸盐酸盐 |
| 英文别名 | 1-Ethyl-6,8-difluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid |
| 规格或纯度 | 10mM in Water |
| 运输条件 | 超低温冰袋运输 |
| 生化机理 | Lomefloxacin is a bactericidal fluoroquinolone agent that is active against gram-negative and gram-positive organisms. Lomefloxacin inhibits bacterial DNA gyrase (topoisomerase II) and topoisomerase IV, which are needed for the transcription and replication of bacterial DNA. DNA gyrase is thought to be the primary quinolone target for gram-negative bacteria. Topoisomerase IV is thought to be the primary target in gram-positive organisms. The inhibition of the topoisomerases results in strand breakage of the bacterial chromosome, supercoiling, and resealing. Therefore, DNA replication and transcription is inhibited. |
一般描述
application：
Lomefloxacin is a fluoroquinolone antibiotic that is commonly used to treat bacterial infections, including bronchitis and urinary tract infections. It is used to induce genomic instability in mice and modification of the kinetics of growth of Gram-negative bacteria.
application：
Lomefloxacin is a fluoroquinolone antibiotic that is commonly used to treat bacterial infections, including bronchitis and urinary tract infections. It is used to induce genomic instability in mice and modification of the kinetics of growth of Gram-negative bacteria.
相关属性
| CAS编号 | 98079-52-8 |
|---|---|
| 储存温度 | -80℃储存 |
| Reaxys-RN | 7506829 |
| RTECS | VB1997500 |
| 分子量 | 387.81 |
| 分子式 | C17H19F2N3O3· HCl |
| 品牌 | Jinpan |
| Smiles | [Cl-].CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNC(C)C3)c(F)c12;Cl.CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNC(C)C3)c(F)c12 |
| PubChem CID | 68624 |