硫酸阿米卡星
氨基糖苷类抗生素。卡那霉素A衍生物。
10mM in Water
有货
基本信息
| 产品名称 | 硫酸阿米卡星 |
|---|---|
| 英文名称 | Amikacin disulfate |
| 别名 | 硫酸阿米卡星；阿米卡星二硫酸盐；O-3-氨基-3-脱氧-α-D-吡喃葡萄糖基-(1→6)O-[6-氨基-6-脱氧-α-D-吡喃葡萄糖基-(1→4)]-N1-[(2S)-4-氨基-2-羟基-1-氧代丁基]-2-脱氧-D-链霉胺硫酸盐；阿米卡星硫酸盐；丁胺卡那霉素硫酸盐 |
| 英文别名 | Amikacin disulfate salt; 4-Amino-N-[5-amino-2-[4-amino-3,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-4-[6-(aminomethyl)-3,4,5-trihydroxy-tetrahydropyran-2-yl]oxy-3-hydroxy-cyclohexyl]-2-hydroxy-butanamide disulfate salt;Amikin sulfate; BAY-41665 |
| 规格或纯度 | 10mM in Water |
| 运输条件 | 超低温冰袋运输 |
| 生化机理 | Amikacin disulfate, also known as BB-K 8, is an aminoglycoside antibiotic that is active against gram-negative bacteria. The activity of Amikacin is similar to that of Kanamycin and Gentamicin. Amikacin has been used in different types of renal studies. We supply the Amikacin disulfate form.Aminoglycoside antibiotic agent. Kanamycin A derivative. Binds to ribosomal RNA. Increases p53-dependent luciferase activation. Shows bactericidal effects. Active in vivo. |
一般描述
Amikacin sulfate是一种半合成，水溶性的卡那霉素氨基糖苷类衍生物 ，可以结合到细菌30S 核糖体亚基上引起mRNA读取错误从而导致细菌不能合成自身生长所必需的蛋白。
Amikacin sulfate binds to 16S rRNA (bacterial 30S ribosome), causing misreading of mRNA and supressing proteins synthesis.
An aminoglycoside antibiotic that is active against gram-negative bacteria
相关属性
| CAS编号 | 39831-55-5 |
|---|---|
| 敏感性 | 对湿度、热敏感 |
| 比旋光度 | +76.0 to +84.0 deg(C=1, water)(calcd.onanh.substance) |
| 熔点 | 220-230°C |
| 储存温度 | -80℃储存 |
| 分子量 | 781.76 |
| 分子式 | C22H43N5O13·2H2SO4 |
| EC号 | 254-648-6 |
| 品牌 | Jinpan |
| PubChem CID | 38351 |