平板素
针对FabF和FabH蛋白的有效抗生素
>99%
有货
基本信息
| 产品名称 | 平板素 |
|---|---|
| 英文名称 | Platencin |
| 规格或纯度 | >99% |
| 运输条件 | 超低温冰袋运输 |
一般描述
平板素是一种抗生素，它是平板霉素的更有效类似物，两者均最初源自| Streptomyces platensis |。机理研究表明，这两种化合物均可抑制细菌脂肪酸的生物合成，这对于细菌的生存至关重要。相对于仅影响FabF的平板霉素，平板素会影响两种对平板霉素抗性细菌有效的蛋白，因为它会影响β-酮酰基-ACP合酶II（FabF）和III（FabH）这两种必需蛋白。
Platencin is an antibiotic that is a more potent analogue of Platensimycin , both of which were originally derived from|Streptomyces platensis|. Mechanistic studies show that both compounds inhibit bacterial fatty acid biosynthesis, which is essential for the survival of bacteria. Platencin may have the potential to be more effective on Platensimycin resistant bacteria, because it affects two essential proteins, β-ketoacyl-ACP synthase II (FabF) and III (FabH), as opposed to Platensymycin, which affects only FabF.
相关属性
| CAS编号 | 869898-86-2 |
|---|---|
| 折光率 | n20D1.65 (Predicted) |
| 沸点 | 670.13° C at 760 mmHg (Predicted) |
| 溶解性 | Soluble in ethanol, methanol, DMSO, DMF, and water (poor). |
| 储存温度 | -20°C储存 |
| 密度 | 1.39 g/cm3(Predicted) |
| 分子量 | 425.47 |
| 分子式 | C24H27NO6 |
| 品牌 | Jinpan |
| Smiles | C[C@@]1(C2C[C@@H]3CC[C@H]2(CC3=C)C=CC1=O)CCC(=O)NC4=C(C=CC(=C4O)C(=O)O)O |
| PubChem CID | 44450228 |