海藻霉素

海藻霉素是一种双链的13员直链肽，具有3,5-二羟基苯丙氨酸和末端二羧酸氨基酸，于1999年从链霉菌中分离出来。海藻霉素是一种有效的抗病毒药物，具有抗菌活性，包括针对MRSA的活性。F海藻霉素特异地抑制MurA和MurC酶，并抑制HIV感染的T细胞，未感染的CD4 + T细胞之间的细胞间转移，以及DC-SIGN介导的病毒向CD4 + T细胞的转移。

Feglymycin is an amphoteric, 13-member, linear peptide featuring 3,5-dihydroxyphenylalanine and a terminal dicarboxylate amino acid, isolated from a|Streptomyces|in 1999. Feglymycin is a potent antiviral agent with antibacterial activity, including against MRSA. Feglymycin specifically inhibits the enzymes MurA and MurC and inhibits cell-to-cell transfer between HIV-infected T cells, uninfected CD4+ T cells, and the DC-SIGN- mediated viral transfer to CD4+ T cells.