蛎灰菌素A
基本信息
| 产品名称 | 蛎灰菌素A |
|---|---|
| 英文名称 | Virginiamycin M1 |
| 别名 | 春霉素 A |
| 应用 | A bacteriostatic inhibitor of translation at the 50S ribosome |
| 规格或纯度 | ≥97% |
| 生化机理 | Virginiamycin M1 inhibits bacterial protein synthesis at the level of aminoacyl-tRNA binding and peptide bond formation. It inactivates the 50S ribosome. S. virginiae inactivates VM1 by reducing its 16-carbonyl group, forming 16R-dihydroVM1. VM1 reductase participates solely in VM1 inactivation in vivo |
一般描述
Ostreogrycin A, also known as Virginiamycin M1, is a streptogramin macrolide antibiotic. Ostreogrycin A interacts with the bacterial 50S ribosome, inhibiting its function in a reversible manner. Activity of Ostreogrycin A at the ribosome blocks translation and produces a bacteriostatic effect. With addition of Virginiamycin S1 , the two antibiotics produce a synergistic bacteriocidal effect. The combination of these compounds, available as a Virginimycin complex , demonstrate efficacy against a broad range of bacteria.A bacteriostatic inhibitor of translation at the 50S ribosome
Ostreogrycin A, also known as Virginiamycin M1, is a streptogramin macrolide antibiotic. Ostreogrycin A interacts with the bacterial 50S ribosome, inhibiting its function in a reversible manner. Activity of Ostreogrycin A at the ribosome blocks translation and produces a bacteriostatic effect. With addition of Virginiamycin S1 , the two antibiotics produce a synergistic bacteriocidal effect. The combination of these compounds, available as a Virginimycin complex , demonstrate efficacy against a broad range of bacteria.
A bacteriostatic inhibitor of translation at the 50S ribosome
相关属性
| CAS编号 | 21411-53-0 |
|---|---|
| 溶解性 | Soluble in water (partly), ethanol (4%), methanol (4%), DMF, and DMSO. |
| 储存温度 | 储存温度-20°C |
| MDL号 | MFCD00869411 |
| 密度 | 1.2600 |
| 分子量 | 525.59 |
| 分子式 | C28H35N3O7 |
| EC号 | 244-376-6 |
| 品牌 | Jinpan |