匹马菌素制剂
基本信息
| 产品名称 | 匹马菌素制剂 |
|---|---|
| 英文名称 | Pimaricin preparation |
| 英文别名 | Natamycin preparation |
| 规格或纯度 | 约2.5%（γ辐照海松霉素）,水悬浮液 |
| 运输条件 | 冰袋运输 |
| 稳定性与储存 | The product is not degraded by a single freeze-thaw cycle. The diluted product should be aliquoted and stored frozen. |
一般描述
Description
This product is a saline suspension with approximately 2.5% pimaricin γ-irradiated.Pimaricin is a polyene antifungal antibiotic produced byStreptomyces natalensisfrom soil near Pietermaritzburg, South Africa.1Pimaricin has antimicrobial activity similar to that of nystatin. In addition, it is active againstTrichomonas vaginalis. Pimaricin is used in the treatment of candidiasis, trichomoniasis, fungal keratitis and aspergillosis. It has also been used as a food additive in some countries. In some studies, it has been shown to decrease the amount of mold upon which theDermatophagoides pteronyssinus(house-dust mite) is dependent.2Pimaricin is an amphoteric antibiotic fromStreptomyces natalensisorS. chattanoogensis. It is used for a variety of fungal infections, mainly topically. It is used as an ergosterol and cholesterol binding agent to study lipid bilayer dynamics, especially in fungal cells. It is used to study pimaricin biosynthesis and as a fungicide in agar media.
Preparation instructions
The product can be further diluted with 0.5 M sodium chloride giving a suspension as well. The product can also be further diluted into an organic solvent such as dimethylformamide (may also be soluble in DMSO).The product and any aqueous dilutions will be suspensions and should not be sterile filtered.
Description
This product is a saline suspension with approximately 2.5% pimaricin γ-irradiated.Pimaricin is a polyene antifungal antibiotic produced byStreptomyces natalensisfrom soil near Pietermaritzburg, South Africa.1Pimaricin has antimicrobial activity similar to that of nystatin. In addition, it is active againstTrichomonas vaginalis. Pimaricin is used in the treatment of candidiasis, trichomoniasis, fungal keratitis and aspergillosis. It has also been used as a food additive in some countries. In some studies, it has been shown to decrease the amount of mold upon which theDermatophagoides pteronyssinus(house-dust mite) is dependent.2Pimaricin is an amphoteric antibiotic fromStreptomyces natalensisorS. chattanoogensis. It is used for a variety of fungal infections, mainly topically. It is used as an ergosterol and cholesterol binding agent to study lipid bilayer dynamics, especially in fungal cells. It is used to study pimaricin biosynthesis and as a fungicide in agar media.
Preparation instructions
The product can be further diluted with 0.5 M sodium chloride giving a suspension as well. The product can also be further diluted into an organic solvent such as dimethylformamide (may also be soluble in DMSO).The product and any aqueous dilutions will be suspensions and should not be sterile filtered.
相关属性
| CAS编号 | 7681-93-8 |
|---|---|
| 熔点 | 280°C（分解） |
| 沸点 | 952°C |
| 溶解性 | DMSO：可溶 |
| 储存温度 | 2-8°C储存 |
| RTECS | TK3325000 |
| MDL号 | MFCD00135085 |
| 密度 | 1.0g/mL at 20°C (lit.) |
| 分子量 | 665.73 |
| 分子式 | C33H47NO13 |
| EC号 | 231-683-5 |
| 品牌 | Jinpan |
| PubChem CID | 5284447 |