STING agonist-7

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STING agonist-7 

STING agonist-7 是一种非核苷酸 STING 激动剂,选择性结合小鼠 STING 而不是人类 STING。STING agonist-7 穿透细胞膜较差。

STING agonist-7

STING agonist-7 Chemical Structure

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生物活性

STING agonist-7 is a non-nucleotide STING agonist. STING agonist-7 binds selectively to mouse STING but not human STING. STING agonist-7 penetrates cell membrane poorly[1].

体外研究
(In Vitro)

STING agonist-7 (compound 11) is active in biochemical assays but inactive in cellular reporter assays[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

336.30

Formula

C17H12N4O4

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Emily C Cherney, et al. Discovery of Non-Nucleotide Small-Molecule STING Agonists via Chemotype Hybridization. J Med Chem. 2022 Feb 24;65(4):3518-3538.

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