上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。
PROTAC AR Degrader-4
PROTAC AR Degrader-4 包含 IAP 配体结合基团,linker 和雄激素受体 (AR) 配体结合基团。基于 cIAP1 的降解剂也被称为 SNIPER。
PROTAC AR Degrader-4 Chemical Structure
CAS No. : 1351169-31-7
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100 mg | 询价 | ||
250 mg | 询价 | ||
500 mg | 询价 |
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PROTAC AR Degrader-4 的其他形式现货产品:
生物活性 |
PROTAC AR Degrader-4 comprises a IAP ligand binding group, a linker and an Androgen Receptor (AR) binding group. PROTAC AR Degrader-4 is an AR degrader. Degradation inducers based on cIAP1 are called specific and non-genetic IAP-dependent protein erasers (SNIPERs)[1]. |
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IC50 & Target[1] |
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体外研究 (In Vitro) |
Specific and Nongenetic IAPs-dependent Protein Erasers (SNIPERs) are bifunctional compounds which are designed by conjugating an IAPs-recognition structure with a target protein-recognition structure. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only. |
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分子量 |
770.01 |
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Formula |
C43H67N3O9 |
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CAS 号 |
1351169-31-7 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
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溶解性数据 |
In Vitro:
DMSO : 200 mg/mL (259.74 mM; Need ultrasonic) 配制储备液
In Vivo:
请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
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参考文献 |
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