上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。
BPK-29
BPK-29 是一种特殊的配体,通过共价修饰 C274 来破坏非典型孤核受体 NR0B1 与 RBM45,SNW1 蛋白质的相互作用。BPK-29 损害 KEAP1 突变癌细胞的锚定独立生长。

BPK-29 Chemical Structure
CAS No. : 2143467-62-1
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BPK-29 的其他形式现货产品:
生物活性 |
BPK-29 is a specific ligand that disrupts the atypical orphan nuclear receptor NR0B1-protein (such RBM45 and SNW1) interactions by covalently modifying C274. BPK-29 impairs the anchorage-independent growth of KEAP1-mutant cancer cells[1]. |
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体外研究 (In Vitro) |
BPK-29 substantially engages NR0B1 with good overall proteomic selectivity in KEAP1-mutant Non-Small Cell Lung Cancers[1]. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only. |
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分子量 |
470.00 |
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Formula |
C26H32ClN3O3 |
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CAS 号 |
2143467-62-1 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
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