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USP30 inhibitor 11
USP30 inhibitor 11 是一个选择性和有效的 USP30 抑制剂，IC50 值为 0.01 µΜ。USP30 inhibitor 11 是例 83，源于专利文献 WO2017009650A1，用于研究癌症和涉及线粒体功能障碍疾病。
USP30 inhibitor 11 Chemical Structure
CAS No. : 2067332-64-1
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| 生物活性 |
USP30 inhibitor 11 is a selective and potent ubiquitin specific peptidase 30 (USP30) inhibitor with an IC50 of 0.01 µΜ, the example 83 extracted from patent WO2017009650A1. USP30 inhibitor 11 is used for the study of cancer and conditions involving mitochondrial dysfunction[1]. |
IC50 & Target |
IC50: 0.01 µΜ (USP30)[1] |
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| 体外研究 (In Vitro) |
USP30 is a 517 amino acid protein which is found in the mitochondrial outer membrane. It is the sole deubiquitylating enzyme bearing a mitochondrial addressing signal and has been shown to deubiquitylate a number of mitochondrial proteins[1].USP30 inhibitor 11 (0.01-30 µΜ; λEx=540 nm; λEm=590 nm) inhibits USP30 biochemical activity with an IC50 of 0.01 µΜ in a USP30 biochemical IC50 assay[1]. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only. |
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| 分子量 |
368.41 |
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| Formula |
C17H16N6O2S |
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| CAS 号 |
2067332-64-1 |
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| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
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| 储存方式 |
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| 参考文献 |
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