L-Norleucine(Synonyms: (S)-2-Aminohexanoic acid; (S)-Norleucine)

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L-Norleucine (Synonyms: (S)-2-Aminohexanoic acid; (S)-Norleucine) 纯度: ≥97.0%

L-Norleucine ((S)-2-Aminohexanoic acid) 是亮氨酸的异构体，能够影响骨骼肌中蛋白质的合成。

L-Norleucine(Synonyms: (S)-2-Aminohexanoic acid; (S)-Norleucine)

L-Norleucine Chemical Structure

CAS No. : 327-57-1

规格 价格 是否有货 数量
10 mM * 1 mL in Water ￥550 In-stock
500 mg ￥500 In-stock
1 g ￥700 In-stock
5 g   询价  
10 g   询价  

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L-Norleucine 相关产品

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生物活性

L-Norleucine ((S)-2-Aminohexanoic acid) is an isomer of leucine, specifically affects protein synthesis in skeletal muscle, and has antivirus activity.

IC50 & Target

Human Endogenous Metabolite

 

体外研究
(In Vitro)

L-Norleucine is an isomer of leucine, specifically affecting protein synthesis in skeletal muscle[1]. L-Norleucine has antiviral activity. L-Norleucine interacts with hnRNPA2/B1 protein to suppresses the expressions of Twist1 and Snail, two inhibitors of E-cadherin, and promotes the expression of E-cadherin, resulting in the inhibition of tumor metastasis[2].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.
Clinical Trial

分子量

131.17

Formula

C6H13NO2
CAS 号

327-57-1
中文名称

L-正亮氨酸
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
溶解性数据
In Vitro: 

H2O : 10 mg/mL (76.24 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 7.6237 mL 38.1185 mL 76.2369 mL
5 mM 1.5247 mL 7.6237 mL 15.2474 mL
10 mM 0.7624 mL 3.8118 mL 7.6237 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
参考文献

  • [1]. Schott KJ, et al. On the role of branched-chain amino acids in protein turnover of skeletal muscle. Studies in vivo with L-norleucine. Z Naturforsch C. 1985 May-Jun;40(5-6):427-37.

    [2]. He T, et al. The homeostasis-maintaining metabolites from bacterial stress response to bacteriophage infection suppress tumor metastasis. Oncogene. 2018 Jun 20.

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