上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。
Abarelix (Synonyms: 阿巴瑞克; R3827; PPI 149) 纯度: 96.27%
Abarelix (R3827) 是有效的促性腺激素释放激素 (GnRH) 拮抗剂,用于研究前列腺癌。
![Abarelix Chemical Structure Abarelix(Synonyms: 阿巴瑞克; R3827; PPI 149)](http://www.fluoroprobe.com/wp-content/uploads/2022/05/hy-13534.gif)
Abarelix Chemical Structure
CAS No. : 183552-38-7
规格 | 价格 | 是否有货 | 数量 |
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10 mM * 1 mL in DMSO | ¥3894 | In-stock | |
5 mg | ¥1500 | In-stock | |
10 mg | ¥2500 | In-stock | |
25 mg | ¥5500 | In-stock | |
50 mg | ¥9500 | 询价 | |
100 mg | 询价 | ||
200 mg | 询价 |
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Abarelix 相关产品
•相关化合物库:
- FDA-Approved Drug Library Mini
生物活性 |
Abarelix (R3827; PPI 149) is a potent gonadotrophin-releasing hormone (GnRH) antagonist, used for prostate cancer treatment. |
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体外研究 (In Vitro) |
Abarelix (30 and 300 µg/mL) causes significantly increased histamine release[1]. Abarelix is the first GnRH antagonist to be developed, and can produce rapid and sustained decreases in testosterone to castrate levels without the need for co-administration of an antiandrogen, and with a very low complication rate in the short term[2]. Abarelix demonstrates to promptly and substantially reduce follicle-stimulating hormone levels to lower than LHRH agonist. Abarelix does not cause a surge in serum testosterone that can precipitate a flare phenomenon or worsening of disease, particularly dangerous for patients with metastatic, symptomatic disease, and produces medical castration more quickly[3]. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only. |
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Clinical Trial |
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分子量 |
1416.06 |
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Formula |
C72H95ClN14O14 |
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CAS 号 |
183552-38-7 |
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Sequence Shortening |
Ac-{d-2-Nal}-{d-4-Cpa}-{d-3-Pal}-S-{NMyr}-{d-Asp}-L-K(ipr)-P-{d-Ala}-NH2 |
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中文名称 |
阿巴瑞克 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
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溶解性数据 |
In Vitro:
DMSO : ≥ 14.2 mg/mL (10.03 mM) * “≥” means soluble, but saturation unknown. 配制储备液
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请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 |
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参考文献 |
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