Triacetylresveratrol(Synonyms: 三乙酰基白藜芦醇)

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Triacetylresveratrol (Synonyms: 三乙酰基白藜芦醇) 纯度: ≥98.0%

Triacetylresveratrol 是 Resveratrol 的乙酰化类似物。Triacetylresveratrol 降低 STAT3 和 NF-κB 磷酸化。具有抗癌作用。

Triacetylresveratrol(Synonyms: 三乙酰基白藜芦醇)

Triacetylresveratrol Chemical Structure

CAS No. : 42206-94-0

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生物活性

Triacetylresveratrol, an acetylated analog of Resveratrol. Triacetylresveratrol decreases the phosphorylation of STAT3 and NF-κB in a dose- and time- dependent manner in PANC-1 and BxPC-3 cells. Anticancer effects[1].

IC50 & Target[1]

NF-κB

 

STAT3

 

体外研究
(In Vitro)

Triacetylresveratrol significantly down-regulates anti-apoptotic Bcl-2 family protein Mcl-1 and up-regulates pro-apoptotic Bcl-2 family proteins Bim and Puma. Triacetylresveratrol inhibits cell viability, and induces apoptosis of pancreatic cancer cells in a concentration and incubation time-dependent manner[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

354.35

Formula

C20H18O6
CAS 号

42206-94-0
中文名称

三乙酰基白藜芦醇
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
溶解性数据
In Vitro: 

DMSO : 125 mg/mL (352.76 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 2.8221 mL 14.1103 mL 28.2207 mL
5 mM 0.5644 mL 2.8221 mL 5.6441 mL
10 mM 0.2822 mL 1.4110 mL 2.8221 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
参考文献

  • [1]. Duan J, et al.  In vitro comparative studies of resveratrol and triacetylresveratrol on cell proliferation, apoptosis, and STAT3 and NFκB signaling in pancreatic cancer cells.Sci Rep. 2016 Aug 19;6:31672.

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