Cytidine-5′-triphosphate(Synonyms: Cytidine triphosphate; 5′-CTP)

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Cytidine-5′-triphosphate (Synonyms: Cytidine triphosphate; 5′-CTP) 纯度: ≥98.0%

Cytidine 5′-triphosphate (Cytidine triphosphate; 5′-CTP) 是一种三磷酸核苷,作为核苷酸和核酸、脂质生物合成的构建砌块。胞嘧啶核苷三磷酸合酶可以催化 UTP 生成 5′-CTP。Cytidine 5′-triphosphate 是 T. gondii 在从头嘧啶生物合成通路中必不可少的生物分子。

Cytidine-5

Cytidine-5′-triphosphate Chemical Structure

CAS No. : 65-47-4

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生物活性

Cytidine 5′-triphosphate (Cytidine triphosphate; 5′-CTP) is a nucleoside triphosphate and serves as a building block for nucleotides and nucleic acids, lipid biosynthesis. Cytidine triphosphate synthase can catalyze the formation of cytidine 5′-triphosphate from uridine 5′-triphosphate (UTP). Cytidine 5′-triphosphate is an essential biomolecule in the de novo pyrimidine biosynthetic pathway in T. gondii[1].

分子量

483.16

Formula

C9H16N3O14P3

CAS 号

65-47-4

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

溶解性数据
In Vitro: 

H2O : 83.33 mg/mL (172.47 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 2.0697 mL 10.3485 mL 20.6971 mL
5 mM 0.4139 mL 2.0697 mL 4.1394 mL
10 mM 0.2070 mL 1.0349 mL 2.0697 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (protect from light)。-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。

参考文献
  • [1]. Heidy Y Narvaez-Ortiz, et al. A CTP Synthase Undergoing Stage-Specific Spatial Expression Is Essential for the Survival of the Intracellular Parasite Toxoplasma gondii. Front Cell Infect Microbiol. 2018 Mar 22;8:83.

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