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(S,R,S)-AHPC-C8-NH2 (Synonyms: VH032-C8-NH2) 纯度: 95.07%
(S,R,S)-AHPC-C8-NH2 (VH032-C8-NH2) 是一种合成的 E3 连接酶配体-linker 偶联物，包含基于 VH032 的 VHL 配体和 1 个 linker。(S,R,S)-AHPC-C8-NH2 可用于合成靶向 AKT 的 PROTAC 降解剂，例 8，XF038-164A，源于专利文献 WO2019173516A1。
(S,R,S)-AHPC-C8-NH2 Chemical Structure
CAS No. : 2341796-79-8
| 规格 | 价格 | 是否有货 | 数量 |
|---|---|---|---|
| 50 mg | ￥5500 | In-stock | |
| 100 mg | ￥8000 | In-stock | |
| 200 mg | 询价 | ||
| 500 mg | 询价 |
* Please select Quantity before adding items.
| 生物活性 |
(S,R,S)-AHPC-C8-NH2 (VH032-C8-NH2) is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used for AKT PROTAC degrader. (S,R,S)-AHPC-C8-NH2 is XF038-164A, example 8, extracted from patent WO2019173516A1[1]. |
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| IC50 & Target |
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| 体外研究 (In Vitro) |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only. |
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| 分子量 |
585.80 |
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| Formula |
C31H47N5O4S |
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| CAS 号 |
2341796-79-8 |
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| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
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| 储存方式 |
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| 参考文献 |
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