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SF488-NH2, Sun Fluor 488 amine Cat. No. SF488-AM-1 Ex/Em:495/520 2 mg修饰性聚乙二醇

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SF488-NH2, Sun Fluor 488 amine

Cat. No. SF488-AM-1
Specification Ex/Em:495/520
Unit Size 2 mg
Price $295.00

Qty Add to Cart

Description:

SFTM fluorophores aim to providing better fluorescent molecular tools for our customers. Besides their superior fluorescent properties, e.g. high brightness, super photo-stability, these fluorophores are designed to simplify your fluorescent labeling and detection process. SFTM fluorophores can be used directly in your aqueous working buffer without need adding any organic solvents. Elimination of organic solvents not only simplifies your labeling and detection process, it also provides additional protection of your molecules from damaging caused by some harsh organic solvents. In addition, SFTM fluorophores offer diversified chemically reactive and/or biologically active moieties that can be used directly for labeling, imaging and detecting of various molecules and particles. These fluorophores range from UV to near IR region and can be used both in-vitro and in-vivo imaging. In short, Nanocs SFTM fluorophores offer following advantages:

  • High fluorescent intensity equal or greater than Alexa fluor or cyanine dyes;
  • High photo-stability with proprietary structure;
  • Good water solubility and no organic solvents needed for labeling.
  • Simplified labeling process with high labeling efficiency.

Specifications:

  • Reactive, fast reaction;
  • Soluble in water;

Storage:

Store at -20 0C.

SF488-NH2, Sun Fluor 488 amine Cat. No. SF488-AM-1 Ex/Em:495/520 2 mg SF488-NH2, Sun Fluor 488 amine Cat. No. SF488-AM-1 Ex/Em:495/520 2 mg SF488-NH2, Sun Fluor 488 amine Cat. No. SF488-AM-1 Ex/Em:495/520 2 mg

SF550-NH2, Sun Fluor 550 amine Cat. No. SF550-AM-1 Ex/Em:554/570 2 mg修饰性聚乙二醇

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上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

SF550-NH2, Sun Fluor 550 amine

Cat. No. SF550-AM-1
Specification Ex/Em:554/570
Unit Size 2 mg
Price $295.00

Qty Add to Cart

Description:

SFTM fluorophores aim to providing better fluorescent molecular tools for our customers. Besides their superior fluorescent properties, e.g. high brightness, super photo-stability, these fluorophores are designed to simplify your fluorescent labeling and detection process. SFTM fluorophores can be used directly in your aqueous working buffer without need adding any organic solvents. Elimination of organic solvents not only simplifies your labeling and detection process, it also provides additional protection of your molecules from damaging caused by some harsh organic solvents. In addition, SFTM fluorophores offer diversified chemically reactive and/or biologically active moieties that can be used directly for labeling, imaging and detecting of various molecules and particles. These fluorophores range from UV to near IR region and can be used both in-vitro and in-vivo imaging. In short, Nanocs SFTM fluorophores offer following advantages:

  • High fluorescent intensity equal or greater than Alexa fluor or cyanine dyes;
  • High photo-stability with proprietary structure;
  • Good water solubility and no organic solvents needed for labeling.
  • Simplified labeling process with high labeling efficiency.

Specifications:

  • Reactive, fast reaction;
  • Soluble in water;

Storage:

Store at -20 0C.

SF550-NH2, Sun Fluor 550 amine Cat. No. SF550-AM-1 Ex/Em:554/570 2 mg SF550-NH2, Sun Fluor 550 amine Cat. No. SF550-AM-1 Ex/Em:554/570 2 mg SF550-NH2, Sun Fluor 550 amine Cat. No. SF550-AM-1 Ex/Em:554/570 2 mg

Lenalidomide-C5-NH2 hydrochloride

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上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

Lenalidomide-C5-NH2 hydrochloride  纯度: 98.45%

Lenalidomide-C5-NH2 hydrochloride 是一种基于 Lenalidomide 的，可募集 CRBN 蛋白的 Cereblon 配体。Lenalidomide-C5-NH2 可通过 linker 与靶蛋白配体连接，形成 PROTAC 分子，比如 MDM2 的PROTAC 降解剂。

Lenalidomide-C5-NH2 hydrochloride

Lenalidomide-C5-NH2 hydrochloride Chemical Structure

规格 价格 是否有货 数量
Free Sample (0.1-0.5 mg)   Apply now  
100 mg ￥4000 In-stock
500 mg ￥9500 In-stock
1 g   询价  
5 g   询价  

* Please select Quantity before adding items.

生物活性

Lenalidomide-C5-NH2 hydrochloride is the Lenalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Lenalidomide-C5-NH2 can be connected to the ligand for protein by a linker to form PROTACs, such as MDM2 PROTAC degrader[1][2].

IC50 & Target

Cereblon

 

分子量

365.85

Formula

C18H24ClN3O3
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
参考文献

  • [1]. Zhou B, et al. Discovery of a Small-Molecule Degrader of Bromodomain and Extra-Terminal (BET) Proteins with Picomolar Cellular Potencies and Capable of Achieving Tumor Regression. J Med Chem. 2018 Jan 25;61(2):462-481.

    [2]. Yangbing Li, et al. Discovery of MD-224 as a First-in-Class, Highly Potent, and Efficacious Proteolysis Targeting Chimera Murine Double Minute 2 Degrader Capable of Achieving Complete and Durable Tumor Regression. J Med Chem. 2019 Jan 24;62(2):448-466.

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(S,R,S)-AHPC-C4-NH2 hydrochloride(Synonyms: VH032-C4-NH2 hydrochloride; VHL Ligand-Linker Conjugates 13; E3 ligase Ligand-Linker Conjugates 28)

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

(S,R,S)-AHPC-C4-NH2 hydrochloride (Synonyms: VH032-C4-NH2 hydrochloride; VHL Ligand-Linker Conjugates 13; E3 ligase Ligand-Linker Conjugates 28) 纯度: 95.35%

(S,R,S)-AHPC-C4-NH2 hydrochloride 是一种合成的 E3 连接酶配体-linker 偶联物，包含基于 (S,R,S)-AHPC 的 VHL 配体和 1 个 linker。用于合成 EED 的靶向PROTAC。

(S,R,S)-AHPC-C4-NH2 hydrochloride(Synonyms: VH032-C4-NH2 hydrochloride; VHL Ligand-Linker Conjugates 13; E3 ligase Ligand-Linker Conjugates 28)

(S,R,S)-AHPC-C4-NH2 hydrochloride Chemical Structure

CAS No. : 2245697-83-8

规格 价格 是否有货 数量
10 mM * 1 mL in DMSO ￥3850 In-stock
100 mg ￥3500 In-stock
500 mg ￥13500 询价
1 g ￥25000 询价
2 g ￥35000 询价
5 g   询价  
10 g   询价  

* Please select Quantity before adding items.

生物活性

(S,R,S)-AHPC-C4-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and a linker used for EED-Targeted PROTAC[1].

IC50 & Target

VHL

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

566.16

Formula

C27H40ClN5O4S
CAS 号

2245697-83-8
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
溶解性数据
In Vitro: 

DMSO : ≥ 109.6 mg/mL (193.58 mM)

H2O : ≥ 50 mg/mL (88.31 mM)

* “≥” means soluble, but saturation unknown.

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 1.7663 mL 8.8314 mL 17.6629 mL
5 mM 0.3533 mL 1.7663 mL 3.5326 mL
10 mM 0.1766 mL 0.8831 mL 1.7663 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
参考文献

  • [1]. Hsu JH, et al. EED-Targeted PROTACs Degrade EED, EZH2, and SUZ12 in the PRC2 Complex. Cell Chem Biol. 2019 Nov 26. pii: S2451-9456(19)30362-9.

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Boc-NH-PEG-NHS Cat. No. PG2-BCNS-5k 5000 Da 1 g修饰性聚乙二醇

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Boc-NH-PEG-NHS

Cat. No. PG2-BCNS-5k
Specification 5000 Da
Unit Size 1 g
Price $385.00

Qty Add to Cart

Description:

Heterobifunctional PEG derivative that can be used to modify proteins, peptides and other materials via amino or other acid reactive chemical groups. PEGylation can increase solubility and stability and reduce immunogenicity of peptides and proteins. It can also suppress the non-specific binding of charged molecules to the modified surfaces.

Physical Properties:

  • Off-white/white solid or viscous liquid depends on molecule weight;
  • Soluble in regular aqeous solution as well as most organic solvents;

Storage Conditions:

  • Store at -20 0C, dessiccated Protect from light. Avoid frequent thaw and freeze.
Documents
  • SDS
  • DataSheet

Boc-NH-PEG-NHS Cat. No. PG2-BCNS-3k 3400 Da 1 g修饰性聚乙二醇

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上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

Boc-NH-PEG-NHS

Cat. No. PG2-BCNS-3k
Specification 3400 Da
Unit Size 1 g
Price $425.00

Qty Add to Cart

Description:

Heterobifunctional PEG derivative that can be used to modify proteins, peptides and other materials via amino or other acid reactive chemical groups. PEGylation can increase solubility and stability and reduce immunogenicity of peptides and proteins. It can also suppress the non-specific binding of charged molecules to the modified surfaces.

Physical Properties:

  • Off-white/white solid or viscous liquid depends on molecule weight;
  • Soluble in regular aqeous solution as well as most organic solvents;

Storage Conditions:

  • Store at -20 0C, dessiccated Protect from light. Avoid frequent thaw and freeze.
Documents
  • SDS
  • DataSheet

SF650-NH2, Sun Fluor 650 amine Cat. No. SF650-AM-1 Ex/Em:650/670 2 mg修饰性聚乙二醇

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上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

SF650-NH2, Sun Fluor 650 amine

Cat. No. SF650-AM-1
Specification Ex/Em:650/670
Unit Size 2 mg
Price $295.00

Qty Add to Cart

Description:

SFTM fluorophores aim to providing better fluorescent molecular tools for our customers. Besides their superior fluorescent properties, e.g. high brightness, super photo-stability, these fluorophores are designed to simplify your fluorescent labeling and detection process. SFTM fluorophores can be used directly in your aqueous working buffer without need adding any organic solvents. Elimination of organic solvents not only simplifies your labeling and detection process, it also provides additional protection of your molecules from damaging caused by some harsh organic solvents. In addition, SFTM fluorophores offer diversified chemically reactive and/or biologically active moieties that can be used directly for labeling, imaging and detecting of various molecules and particles. These fluorophores range from UV to near IR region and can be used both in-vitro and in-vivo imaging. In short, Nanocs SFTM fluorophores offer following advantages:

  • High fluorescent intensity equal or greater than Alexa fluor or cyanine dyes;
  • High photo-stability with proprietary structure;
  • Good water solubility and no organic solvents needed for labeling.
  • Simplified labeling process with high labeling efficiency.

Specifications:

  • Reactive, fast reaction;
  • Soluble in water;

Storage:

Store at -20 0C.

SF650-NH2, Sun Fluor 650 amine Cat. No. SF650-AM-1 Ex/Em:650/670 2 mg SF650-NH2, Sun Fluor 650 amine Cat. No. SF650-AM-1 Ex/Em:650/670 2 mg SF650-NH2, Sun Fluor 650 amine Cat. No. SF650-AM-1 Ex/Em:650/670 2 mg

Boc-NH-PEG-NHS Cat. No. PG2-BCNS-2k 2000 Da 1 g修饰性聚乙二醇

发表于由

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

Boc-NH-PEG-NHS

Cat. No. PG2-BCNS-2k
Specification 2000 Da
Unit Size 1 g
Price $485.00

Qty Add to Cart

Description:

Heterobifunctional PEG derivative that can be used to modify proteins, peptides and other materials via amino or other acid reactive chemical groups. PEGylation can increase solubility and stability and reduce immunogenicity of peptides and proteins. It can also suppress the non-specific binding of charged molecules to the modified surfaces.

Physical Properties:

  • Off-white/white solid or viscous liquid depends on molecule weight;
  • Soluble in regular aqeous solution as well as most organic solvents;

Storage Conditions:

  • Store at -20 0C, dessiccated Protect from light. Avoid frequent thaw and freeze.
Documents
  • SDS
  • DataSheet

Boc-NH-PEG3(Synonyms: PROTAC Linker 10)

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

Boc-NH-PEG3 (Synonyms: PROTAC Linker 10) 纯度: ≥95.0%

Boc-NH-PEG3 (PROTAC Linker 10) 是一种 PROTAC linker，属于 PEG 类。Boc-NH-PEG3 可用于合成 PROTAC 分子。

Boc-NH-PEG3(Synonyms: PROTAC Linker 10)

Boc-NH-PEG3 Chemical Structure

CAS No. : 139115-92-7

规格 价格 是否有货 数量
100 mg ￥800 In-stock
200 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Boc-NH-PEG3 (PROTAC Linker 10) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

249.30

Formula

C11H23NO5
CAS 号

139115-92-7
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
参考文献

  • [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

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Macropa-NH2 hydrochloride

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

Macropa-NH2 hydrochloride  纯度: 98.81%

Macropa-NH2 hydrochloride 是 Macropa-NCS 的前体。Macropa-NCS 能与曲妥珠单抗 (HY-P9907) 以及前列腺特异性膜抗原靶向化合物 RPS-070 结合，可用于软组织转移瘤的研究。

Macropa-NH2 hydrochloride

Macropa-NH2 hydrochloride Chemical Structure

CAS No. : 2443966-86-5

规格 价格 是否有货 数量
5 mg ￥5000 In-stock
10 mg ￥8500 In-stock
25 mg ￥17500 In-stock
50 mg ￥28500 In-stock
100 mg ￥45000 In-stock
200 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

Macropa-NH2 hydrochloride 相关产品

•相关化合物库:

  • Bioactive Compound Library Plus
  • Anti-Cancer Compound Library

生物活性

Macropa-NH2 hydrochloride is the precursor of Macropa-NCS. Macropa-NCS is conjugated to Anti-Human HER2 (HY-P9907) as well as to the prostate-specific membrane antigen-targeting compound RPS-070 and is a promising therapeutic radionuclide applied in the treatment of soft-tissue metastases[1].

体外研究
(In Vitro)

A white suspension of 11•4TFA (0.1598 g, 0.16 mmol) and Na2CO3 (0.2540 g, 2.4 mmol) was heated at reflux in acetone (10 mL) for 30 min before the slow addition of CSCl2 (305 µL of CSCl2, 85%, Acros Organics). The resulting orange suspension was heated at reflux for 3 h and then concentrated at 30 °C under reduced pressure to a pale-orange solid. The solid was dissolved portionwise in 10% ACN/H2O containing 0.2% TFA (8 mL total), filtered, and immediately purified by preparative HPLC using Method C. Pure fractions were combined, concentrated at RT under reduced pressure to remove the organic solvent, and then lyophilized. Fractions that were not able to be concentrated immediately were frozen at -80 °C. Isothiocyanate 12 was obtained as a mixture of white and pale-yellow solid (0.0547 g) and was stored at –80 °C in a jar of Drierite. A stock solution containing 4.4 mg/mL of macropa-NCS was prepared in 0.1 M pH 9.1 NaHCO3 buffer containing 0.154 M NaCl and was stored at -80 °C. To a portion of Tmab in saline (74 μL) were added macropa-NCS (52 μL) and NaHCO3 buffer (266 μL), so that the final concentrations of Tmab and macropa-NCS were 5.1 mg/mL and 0.59 mg/mL, respectively. Macropa-NCS was estimated to be in 16-fold molar excess to Tmab based on a molecular weight of 1045.76 g/mol for macropa-NCS (tetra-TFA salt)[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

584.06

Formula

C26H38ClN5O8
CAS 号

2443966-86-5
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
溶解性数据
In Vitro: 

DMSO : 83.33 mg/mL (142.67 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 1.7122 mL 8.5608 mL 17.1215 mL
5 mM 0.3424 mL 1.7122 mL 3.4243 mL
10 mM 0.1712 mL 0.8561 mL 1.7122 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

In Vivo:

请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液，再依次添加助溶剂：

——为保证实验结果的可靠性，澄清的储备液可以根据储存条件，适当保存；体内实验的工作液，建议您现用现配，当天使用； 以下溶剂前显示的百
分比是指该溶剂在您配制终溶液中的体积占比；如在配制过程中出现沉淀、析出现象，可以通过加热和/或超声的方式助溶

  • 1.

    请依序添加每种溶剂： 10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.08 mg/mL (3.56 mM); Clear solution

    此方案可获得 ≥ 2.08 mg/mL (3.56 mM，饱和度未知) 的澄清溶液。

    以 1 mL 工作液为例，取 100 μL 20.8 mg/mL 的澄清 DMSO 储备液加到 400 μL PEG300 中，混合均匀；向上述体系中加入50 μL Tween-80，混合均匀；然后继续加入 450 μL生理盐水定容至 1 mL。

    将 0.9 g 氯化钠，完全溶解于 100 mL ddH₂O 中，得到澄清透明的生理盐水溶液

  • 2.

    请依序添加每种溶剂： 10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.08 mg/mL (3.56 mM); Clear solution

    此方案可获得 ≥ 2.08 mg/mL (3.56 mM，饱和度未知) 的澄清溶液。

    以 1 mL 工作液为例，取 100 μL 20.8 mg/mL 的澄清 DMSO 储备液加到 900 μL 20% 的 SBE-β-CD 生理盐水水溶液中，混合均匀。

    将 2 g 磺丁基醚 β-环糊精加入 5 mL 生理盐水中，再用生理盐水定容至 10 mL，完全溶解，澄清透明
  • 3.

    请依序添加每种溶剂： 10% DMSO    90% corn oil

    Solubility: ≥ 2.08 mg/mL (3.56 mM); Clear solution

    此方案可获得 ≥ 2.08 mg/mL (3.56 mM，饱和度未知) 的澄清溶液，此方案不适用于实验周期在半个月以上的实验。

    以 1 mL 工作液为例，取 100 μL 20.8 mg/mL 的澄清 DMSO 储备液加到 900 μL玉米油中，混合均匀。

*以上所有助溶剂都可在 上海金畔生物科技有限公司 网站选购。
参考文献

  • [1]. Thiele NA, et al. An Eighteen-Membered Macrocyclic Ligand for Actinium-225 Targeted Alpha Therapy. Angew Chem Int Ed Engl. 2017 Nov 13;56(46):14712-14717.

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NH2-C2-NH-Boc(Synonyms: PROTAC Linker 22)

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

NH2-C2-NH-Boc (Synonyms: PROTAC Linker 22) 纯度: ≥97.0%

NH2-C2-NH-Boc (PROTAC Linker 22) 是一种 PROTAC linker，属于 alkyl chain 类。NH2-C2-NH-Boc 可用于合成 PROTAC 分子。

NH2-C2-NH-Boc(Synonyms: PROTAC Linker 22)

NH2-C2-NH-Boc Chemical Structure

CAS No. : 57260-73-8

规格 价格 是否有货 数量
100 mg ￥500 In-stock
200 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

NH2-C2-NH-Boc (PROTAC Linker 22) is a alkyl chain-based PROTAC linker can be used in the synthesis of PROTACs[1].

IC50 & Target[1]

Alkyl-Chain

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

160.21

Formula

C7H16N2O2
CAS 号

57260-73-8
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
参考文献

  • [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

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Fmoc-NH-PEG4-CH2CH2COOH(Synonyms: Fmoc-15-amino-4,7,10,13-tetraoxapentadecanoic acid)

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

Fmoc-NH-PEG4-CH2CH2COOH (Synonyms: Fmoc-15-amino-4,7,10,13-tetraoxapentadecanoic acid) 纯度: 98.03%

Fmoc-NH-PEG4-CH2CH2COOH 是一种可降解的 ADC linker，用于抗体药物偶联物 (ADC) 合成。Fmoc-NH-PEG4-CH2CH2COOH 也是一种基于 PEG 的 PROTAC linker，可用于 PROTAC 的合成。

Fmoc-NH-PEG4-CH2CH2COOH(Synonyms: Fmoc-15-amino-4,7,10,13-tetraoxapentadecanoic acid)

Fmoc-NH-PEG4-CH2CH2COOH Chemical Structure

CAS No. : 557756-85-1

规格 价格 是否有货 数量
Free Sample (0.1-0.5 mg)   Apply now  
100 mg ￥500 In-stock
200 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Fmoc-NH-PEG4-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-NH-PEG4-CH2CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

Cleavable

 

PEGs

 

体外研究
(In Vitro)

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

487.54

Formula

C26H33NO8
CAS 号

557756-85-1
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
溶解性数据
In Vitro: 

DMSO : 100 mg/mL (205.11 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 2.0511 mL 10.2556 mL 20.5111 mL
5 mM 0.4102 mL 2.0511 mL 4.1022 mL
10 mM 0.2051 mL 1.0256 mL 2.0511 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

In Vivo:

请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液，再依次添加助溶剂：

——为保证实验结果的可靠性，澄清的储备液可以根据储存条件，适当保存；体内实验的工作液，建议您现用现配，当天使用； 以下溶剂前显示的百
分比是指该溶剂在您配制终溶液中的体积占比；如在配制过程中出现沉淀、析出现象，可以通过加热和/或超声的方式助溶

  • 1.

    请依序添加每种溶剂： 10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (5.13 mM); Clear solution

    此方案可获得 ≥ 2.5 mg/mL (5.13 mM，饱和度未知) 的澄清溶液。

    以 1 mL 工作液为例，取 100 μL 25.0 mg/mL 的澄清 DMSO 储备液加到 400 μL PEG300 中，混合均匀；向上述体系中加入50 μL Tween-80，混合均匀；然后继续加入 450 μL生理盐水定容至 1 mL。

    将 0.9 g 氯化钠，完全溶解于 100 mL ddH₂O 中，得到澄清透明的生理盐水溶液

  • 2.

    请依序添加每种溶剂： 10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (5.13 mM); Clear solution

    此方案可获得 ≥ 2.5 mg/mL (5.13 mM，饱和度未知) 的澄清溶液。

    以 1 mL 工作液为例，取 100 μL 25.0 mg/mL 的澄清 DMSO 储备液加到 900 μL 20% 的 SBE-β-CD 生理盐水水溶液中，混合均匀。

    将 2 g 磺丁基醚 β-环糊精加入 5 mL 生理盐水中，再用生理盐水定容至 10 mL，完全溶解，澄清透明
  • 3.

    请依序添加每种溶剂： 10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (5.13 mM); Clear solution

    此方案可获得 ≥ 2.5 mg/mL (5.13 mM，饱和度未知) 的澄清溶液，此方案不适用于实验周期在半个月以上的实验。

    以 1 mL 工作液为例，取 100 μL 25.0 mg/mL 的澄清 DMSO 储备液加到 900 μL玉米油中，混合均匀。

*以上所有助溶剂都可在 上海金畔生物科技有限公司 网站选购。
参考文献

  • [1]. Cai P, et al. Synthesis of C3-Alkylated Indoles on DNA via Indolyl Alcohol Formation Followed by Metal-FreeTransfer Hydrogenation. Org Lett. 2019 Aug 14.

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Thalidomide-NH-C6-NH2 TFA

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

Thalidomide-NH-C6-NH2 TFA  纯度: 99.82%

Thalidomide-NH-C6-NH2 TFA是一种合成的 E3 连接酶配体 -linker 偶联物，包含基于 Thalidomide 的 cereblon 配体和 1 个 linker。

Thalidomide-NH-C6-NH2 TFA

Thalidomide-NH-C6-NH2 TFA Chemical Structure

CAS No. : 2093386-51-5

规格 价格 是否有货 数量
Free Sample (0.1-0.5 mg)   Apply now  
100 mg ￥5500 In-stock
250 mg ￥9800 In-stock
500 mg ￥13500 In-stock
1 g   询价  
5 g   询价  

* Please select Quantity before adding items.

生物活性

Thalidomide-NH-C6-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1].

IC50 & Target

Cereblon

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

486.44

Formula

C21H25F3N4O6
CAS 号

2093386-51-5
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

-20°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
参考文献

  • [1]. Wang Z, et al. Proteolysis Targeting Chimeras for the Selective Degradation of Mcl-1/Bcl-2 Derived from Nonselective Target Binding Ligands. J Med Chem. 2019 Sep 12;62(17):8152-8163.

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Tos-PEG4-NH-Boc(Synonyms: PROTAC Linker 7)

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

Tos-PEG4-NH-Boc (Synonyms: PROTAC Linker 7)

Tos-PEG4-NH-Boc (PROTAC Linker 7) 是一种 PROTAC linker，属于 PEG 类。Tos-PEG4-NH-Boc 可用于合成 PROTAC 分子。

Tos-PEG4-NH-Boc(Synonyms: PROTAC Linker 7)

Tos-PEG4-NH-Boc Chemical Structure

CAS No. : 1246999-33-6

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

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生物活性

Tos-PEG4-NH-Boc (PROTAC Linker 7) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

IC50 & Target

Alkyl/ether

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

447.54

Formula

C20H33NO8S
CAS 号

1246999-33-6
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

NH2-PEG5-C2-NH-Boc(Synonyms: PROTAC Linker 17)

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

NH2-PEG5-C2-NH-Boc (Synonyms: PROTAC Linker 17)

NH2-PEG5-C2-NH-Boc (PROTAC Linker 17) 是一种 PROTAC linker，属于 PEG 类。NH2-PEG5-C2-NH-Boc 可用于合成 PROTAC 分子。

NH2-PEG5-C2-NH-Boc(Synonyms: PROTAC Linker 17)

NH2-PEG5-C2-NH-Boc Chemical Structure

CAS No. : 189209-27-6

规格 价格 是否有货 数量
100 mg ￥1100 In-stock
200 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

NH2-PEG5-C2-NH-Boc (PROTAC Linker 17) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

Alkyl/ether

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

380.48

Formula

C17H36N2O7
CAS 号

189209-27-6
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
参考文献

  • [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

HSDVHK-NH2

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

HSDVHK-NH2  纯度: 99.63%

HSDVHK-NH2 是整合素 αvβ3-玻璃体结合蛋白的互作抑制剂，其 IC50 值为 1.74 pg/mL (2.414 pM)。

HSDVHK-NH2

HSDVHK-NH2 Chemical Structure

CAS No. : 848644-86-0

规格 价格 是否有货 数量
5 mg ￥1800 In-stock
10 mg ￥3100 In-stock
50 mg   询价  
100 mg   询价  

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HSDVHK-NH2 相关产品

•相关化合物库:

  • Bioactive Compound Library Plus
  • Immunology/Inflammation Compound Library
  • Anti-Cancer Compound Library
  • Cytoskeleton Compound Library
  • Targeted Diversity Library
  • Peptide Library

生物活性

HSDVHK-NH2 is an antagonist of the integrin αvβ3-vitronectin interaction, with an IC50 of 1.74 pg/mL (2.414 pM)[1][2].

IC50 & Target

αvβ3

2.74 nM (IC50)

体外研究
(In Vitro)

HSDVHK significantly inhibited bFGF-induced cell migration compared to the PBS control group[1].
The Arg-Gly-Asp (RGD)-binding site recognition by HSDVHK-NH2 (P11) is site specific because the HSDVHK-NH2 (P11) is inactive for the complex formation of a denatured form of integrin–vitronectin. HSDVHK-NH2 (P11) shows a strong antagonism against avb3-GRGDSP interaction with an IC50 value of 25.72 nM[2].
HSDVHK-NH2 (P11) inhibits the HUVEC proliferation due to the induction of HUVEC cell death through caspases activations and its mechanism is related with increased p53 expression[3].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Proliferation Assay[3]

Cell Line: HUVEC cells.
Concentration: 0.1, 1, 10, and 100 μg/mL.
Incubation Time: 72 h.
Result: Significantly inhibited HUVEC proliferation on denatured collagen-coated plates in a dose-dependent manner.

分子量

720.78

Formula

C30H48N12O9
CAS 号

848644-86-0
Sequence Shortening

HSDVHK-NH2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Protect from light

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
溶解性数据
In Vitro: 

H2O : 250 mg/mL (346.85 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 1.3874 mL 6.9369 mL 13.8739 mL
5 mM 0.2775 mL 1.3874 mL 2.7748 mL
10 mM 0.1387 mL 0.6937 mL 1.3874 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (protect from light)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
参考文献

  • [1]. Yoonsuk Lee, et al. High-throughput screening of novel peptide inhibitors of an integrin receptor from the hexapeptide library by using a protein microarray chip. J Biomol Screen. 2004 Dec;9(8):687-94.

    [2]. Youngjin Choi, et al. Site-specific inhibition of integrin alpha v beta 3-vitronectin association by a ser-asp-val sequence through an Arg-Gly-Asp-binding site of the integrin. Proteomics. 2010 Jan;10(1):72-80.

    [3]. Ji-Young Bang, et al. Pharmacoproteomic analysis of a novel cell-permeable peptide inhibitor of tumor-induced angiogenesis. Mol Cell Proteomics. 2011 Aug;10(8):M110.005264.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

NH2-PEG2-C6-Cl

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

NH2-PEG2-C6-Cl  纯度: ≥95.0%

NH2-PEG2-C6-Cl 是一种 PROTAC linker，属于 PEG 类。可用于合成 PROTAC 分子。

NH2-PEG2-C6-Cl

NH2-PEG2-C6-Cl Chemical Structure

CAS No. : 744203-60-9

规格 价格 是否有货 数量
50 mg ￥1350 In-stock
100 mg ￥1980 In-stock
200 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

NH2-PEG2-C6-Cl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

223.74

Formula

C10H22ClNO2
CAS 号

744203-60-9
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

-20°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
溶解性数据
In Vitro: 

DMSO : 100 mg/mL (446.95 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 4.4695 mL 22.3474 mL 44.6947 mL
5 mM 0.8939 mL 4.4695 mL 8.9389 mL
10 mM 0.4469 mL 2.2347 mL 4.4695 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

In Vivo:

请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液，再依次添加助溶剂：

——为保证实验结果的可靠性，澄清的储备液可以根据储存条件，适当保存；体内实验的工作液，建议您现用现配，当天使用； 以下溶剂前显示的百
分比是指该溶剂在您配制终溶液中的体积占比；如在配制过程中出现沉淀、析出现象，可以通过加热和/或超声的方式助溶

  • 1.

    请依序添加每种溶剂： 10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (11.17 mM); Clear solution

    此方案可获得 ≥ 2.5 mg/mL (11.17 mM，饱和度未知) 的澄清溶液。

    以 1 mL 工作液为例，取 100 μL 25.0 mg/mL 的澄清 DMSO 储备液加到 400 μL PEG300 中，混合均匀；向上述体系中加入50 μL Tween-80，混合均匀；然后继续加入 450 μL生理盐水定容至 1 mL。

    将 0.9 g 氯化钠，完全溶解于 100 mL ddH₂O 中，得到澄清透明的生理盐水溶液

  • 2.

    请依序添加每种溶剂： 10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (11.17 mM); Clear solution

    此方案可获得 ≥ 2.5 mg/mL (11.17 mM，饱和度未知) 的澄清溶液。

    以 1 mL 工作液为例，取 100 μL 25.0 mg/mL 的澄清 DMSO 储备液加到 900 μL 20% 的 SBE-β-CD 生理盐水水溶液中，混合均匀。

    将 2 g 磺丁基醚 β-环糊精加入 5 mL 生理盐水中，再用生理盐水定容至 10 mL，完全溶解，澄清透明
  • 3.

    请依序添加每种溶剂： 10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (11.17 mM); Clear solution

    此方案可获得 ≥ 2.5 mg/mL (11.17 mM，饱和度未知) 的澄清溶液，此方案不适用于实验周期在半个月以上的实验。

    以 1 mL 工作液为例，取 100 μL 25.0 mg/mL 的澄清 DMSO 储备液加到 900 μL玉米油中，混合均匀。

*以上所有助溶剂都可在 上海金畔生物科技有限公司 网站选购。
参考文献

  • [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Bis-NH2-C1-PEG3(Synonyms: PROTAC Linker 24)

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

Bis-NH2-C1-PEG3 (Synonyms: PROTAC Linker 24)

Bis-NH2-C1-PEG3 (PROTAC Linker 24) 是一种 PROTAC linker，属于 PEG 类。Bis-NH2-C1-PEG3 可用于合成 PROTAC 分子。

Bis-NH2-C1-PEG3(Synonyms: PROTAC Linker 24)

Bis-NH2-C1-PEG3 Chemical Structure

CAS No. : 4246-51-9

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Bis-NH2-C1-PEG3 (PROTAC Linker 24) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

IC50 & Target[1]

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

220.31

Formula

C10H24N2O3
CAS 号

4246-51-9
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
参考文献

  • [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Tos-PEG2-NH2(Synonyms: PROTAC Linker 27)

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

Tos-PEG2-NH2 (Synonyms: PROTAC Linker 27)

Tos-PEG2-NH2 (PROTAC Linker 27) 是一种 PROTAC linker，属于 PEG 类。Tos-PEG2-NH2 可用于合成 PROTAC 分子。

Tos-PEG2-NH2(Synonyms: PROTAC Linker 27)

Tos-PEG2-NH2 Chemical Structure

CAS No. : 1246286-33-8

规格 价格 是否有货
50 mg ￥2500 询问价格 & 货期
100 mg ￥4500 询问价格 & 货期
250 mg ￥9500 询问价格 & 货期

* Please select Quantity before adding items.

生物活性

Tos-PEG2-NH2 (PROTAC Linker 27) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

IC50 & Target[1]

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

259.32

Formula

C11H17NO4S
CAS 号

1246286-33-8
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Boc-NH-PEG-NH2 Cat. No. PG2-AMBC-3k 3400 Da 1 g修饰性聚乙二醇

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上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

Boc-NH-PEG-NH2

Cat. No. PG2-AMBC-3k
Specification 3400 Da
Unit Size 1 g
Price $385.00

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https://scholar.google.com/scholar?hl=en&as_sdt=0%2C22&q=Nanocs+PEG&btnG=Description:

Boc-NH-PEG-NH2 (Boc PEG amine) is one of Nanocs' heterobifunctional PEG derivative that can be used to modify proteins, peptides and other materials via amino or other acid reactive chemical groups. t-Boc protect group in this Boc-PEG-amine compound can be easily deprotected under acidic condition to release free amine for further reaction.

Physical Properties:

  • Off-white/white solid or viscous liquid depends on molecule weight;
  • Soluble in regular aqeous solution as well as most organic solvents;

Storage Conditions:

  • Store at 4 0C or lower.

References:

Click here to see hundreds of publications from Nanocs PEGs.

Documents
  • SDS
  • DataSheet